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可生物降解环二尖瓣成形术治疗感染性心内膜炎:外科医生用于儿童瓣膜修复的新工具。

Mitral annuloplasty with biodegradable ring for infective endocarditis: a new tool for the surgeon for valve repair in childhood.

作者信息

Kazaz Hakki, Celkan Mehmet Adnan, Ustunsoy Hasim, Baspinar Osman

机构信息

Department of Cardiovascular Surgery, Gaziantep University, School of Medicine, Ulus mah 37 nolu sokak, Cumhuriyet Apt. No:11/5, Sehitkamil Gaziantep, Turkey.

出版信息

Interact Cardiovasc Thorac Surg. 2005 Aug;4(4):378-80. doi: 10.1510/icvts.2005.105833. Epub 2005 May 27.

Abstract

The incidence of bacterial endocarditis and valvular involvement is rare in the childhood period. If the patient is unresponsive to medical treatment and some complications occur, early surgical treatment is indicated. Debridement of vegetation combined with valve repair techniques sparing the native valve is the ideal surgical procedure instead of replacement, especially for children. Annuloplasty is the key step during valve repair procedures. On the other hand, absence of appropriate sized annuloplasty rings on the market for this group of patients is the main problem. Nondegradable annuloplasty rings might lead to stenosis as the child grows. Thus, biodegradable tissue engineered materials are new solutions for such patients since the fibrous tissue induced by implanted ring grows with time. We describe a pediatric patient with Brucella endocarditis at the mitral position who was treated successfully with valve repair using a biodegradable annuloplasty ring (Kalangos Biodegradable Ring).

摘要

细菌性心内膜炎及瓣膜受累在儿童期的发生率很低。若患者对药物治疗无反应且出现一些并发症,则需早期手术治疗。清除赘生物并结合保留自体瓣膜的瓣膜修复技术是理想的手术方式,而非瓣膜置换,尤其对于儿童患者。瓣环成形术是瓣膜修复手术的关键步骤。另一方面,市场上缺乏适合该类患者尺寸的瓣环成形环是主要问题。不可降解的瓣环成形环可能会随着孩子生长导致狭窄。因此,可生物降解的组织工程材料是这类患者的新解决方案,因为植入环诱导的纤维组织会随时间生长。我们描述了一名二尖瓣位布鲁氏菌性心内膜炎的儿科患者,其使用可生物降解瓣环成形环(卡朗戈斯可生物降解环)成功接受了瓣膜修复治疗。

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