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在接受心脏手术的患者中,胸段硬膜外镇痛联合全身麻醉可使恢复更快且并发症更少,但不影响住院时间。

In patients undergoing cardiac surgery, thoracic epidural analgesia combined with general anaesthesia results in faster recovery and fewer complications but does not affect length of hospital stay.

作者信息

Ronald Andrew, Abdulaziz K Anuar, Day Thomas George, Scott Martin

机构信息

Department of Cardiac Anaesthesia, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN, UK.

出版信息

Interact Cardiovasc Thorac Surg. 2006 Jun;5(3):207-16. doi: 10.1510/icvts.2005.125054. Epub 2005 Dec 13.

Abstract

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether the use of thoracic epidural anaesthesia (TEA) in combination with general anaesthesia during adult cardiac surgery resulted in a faster recovery, fewer complications and shorter length of hospital stay. Altogether 313 papers were identified on Medline and 368 on Embase using the reported search of which 15 represented the best evidence on the topic. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses were tabulated. We conclude that the use of TEA in combination with general anaesthesia results in more rapid extubation and significantly better pain relief in patients undergoing cardiac surgery. In addition, common postoperative complications such as chest infection, dysrhythmia, confusional states, renal failure and psychological sequelae may be decreased although there is currently no evidence that its use decreases length of hospital stay. Finally, whilst there are case reports of neurological injury secondary to epidural haematoma in the literature these are rare and a number of large studies have been performed confirming the safety of the technique when basic precautions regarding technical aspects of the procedure and coagulation management are followed.

摘要

根据结构化方案撰写了一篇心脏外科的最佳证据主题文章。所探讨的问题是,在成人心脏手术中,胸段硬膜外麻醉(TEA)与全身麻醉联合使用是否能带来更快的恢复、更少的并发症以及更短的住院时间。通过报告的检索,在Medline上共识别出313篇论文,在Embase上识别出368篇论文,其中15篇代表了该主题的最佳证据。将作者、期刊、出版日期和国家、所研究的患者群体、研究类型、相关结果、研究结果以及研究的不足之处制成表格。我们得出结论,在接受心脏手术的患者中,TEA与全身麻醉联合使用可使拔管更快,疼痛缓解明显更好。此外,虽然目前没有证据表明其使用能缩短住院时间,但常见的术后并发症如肺部感染、心律失常、意识混乱状态、肾衰竭和心理后遗症可能会减少。最后,虽然文献中有硬膜外血肿继发神经损伤的病例报告,但这些情况很少见,并且已经进行了一些大型研究,证实了在遵循关于手术技术方面和凝血管理的基本预防措施时该技术的安全性。

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