Crespi-Porro R, Conti A, Cabella R
Servizio di Radiologia, Ospedale Generale Provinciale, Saronno, Varese.
Radiol Med. 1991 Oct;82(4):480-3.
Two different volumes of iopamidol (250 and 100 ml, respectively) containing 37.5 and 37 g of iodine in different concentrations (150 mgI/ml and 370 mgI/ml) were injected in the same time (10 minutes) with varying injection rates, to compare diagnostic effectiveness, image quality, distension of the collecting system, and influence of the better iodine concentration. Sixty patients of both sexes were randomly subdivided into two groups. Their renal function, blood pressure and pulse rate were normal. Their weight ranged 55-85 kg, not to change the distribution volume of the contrast medium. None of them had been given iodine compounds recently. Radiographs were taken 2, 5, 15, 25, and 30 minutes after the end of the injection. The image quality of nephrograms, pyelograms, bladder views and the degree of collecting system filling were evaluated by a blind study, using grading scores (0 to 3). In both groups image quality and degree of filling were satisfying; the volume of injected iopamidol had poor significance. The clinical findings confirm that, with a nonionic contrast medium, iodine concentration in the collecting system is the most important factor for image quality.
分别注射两种不同体积的碘帕醇（分别为250毫升和100毫升），含碘量分别为37.5克和37克，浓度不同（150毫克碘/毫升和370毫克碘/毫升），在相同时间（10分钟）内以不同注射速率注射，以比较诊断效果、图像质量、集合系统的扩张情况以及更佳碘浓度的影响。60名男女患者被随机分为两组。他们的肾功能、血压和脉搏率均正常。体重范围为55至85千克，以不改变造影剂的分布容积。他们近期均未使用过碘化合物。在注射结束后2、5、15、25和30分钟拍摄X光片。通过盲法研究，使用分级评分（0至3）评估肾图、肾盂造影、膀胱影像的图像质量以及集合系统的充盈程度。两组的图像质量和充盈程度均令人满意；注射的碘帕醇体积影响不大。临床结果证实，对于非离子型造影剂，集合系统中的碘浓度是影响图像质量的最重要因素。
