Shah H, Kniestedt C, Bostrom A, Stamper R, Lin S
Department of Glaucoma, University of California-San Francisco, San Francisco, CA, USA.
Eur J Ophthalmol. 2007 Jul-Aug;17(4):545-9. doi: 10.1177/112067210701700411.
To evaluate the relationship of central corneal thickness (CCT) to baseline visual field parameters and visual field progression in patients with primary open-angle glaucoma (POAG).
Charts of consecutive patients with POAG were reviewed to obtain visual field data. Visual field was measured by standard threshold static perimetry. Variables analyzed included mean deviation (MD) and pattern standard deviation (PSD).
A total of 121 eyes examined over 4 years were evaluated. A significant negative relationship between CCT and PSD (correlation coefficient: -0.02, p<0.05) was found. Analyses comparing CCT to change in PSD and MD (visual field progression) were statistically not significant.
Patients with thinner corneas initially present with a greater visual field defect, indicating that thin corneas may contribute to advanced glaucomatous damage at the time of diagnosis. However, CCT does not seem to be a significant risk factor for progression of the disease.
评估原发性开角型青光眼（POAG）患者的中央角膜厚度（CCT）与基线视野参数及视野进展之间的关系。
回顾连续性POAG患者的病历以获取视野数据。通过标准阈值静态视野计测量视野。分析的变量包括平均偏差（MD）和模式标准偏差（PSD）。
对4年间检查的121只眼进行了评估。发现CCT与PSD之间存在显著负相关（相关系数：-0.02，p<0.05）。比较CCT与PSD和MD变化（视野进展）的分析在统计学上无显著意义。
角膜较薄的患者最初出现的视野缺损更大，这表明薄角膜可能在诊断时就导致了青光眼性损害的进展。然而，CCT似乎不是疾病进展的重要危险因素。
Zotero 插件