Xiao Wei, Liang Xiao-Fang, Sun Jia-Jun
Department of Ophthalmology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.
Int J Ophthalmol. 2011;4(1):78-80. doi: 10.3980/j.issn.2222-3959.2011.01.18. Epub 2011 Feb 18.
To observe the central corneal thickness (CCT) changes in infants and young children who had been undergone bilateral congenital cataract surgery, and to compare the changes with normal control group which was selected from healthy population.
A cross section case-control study contained 28 cases (56 eyes) of bilateral aphakia (aphakic group) due to congenital cataract surgery combining with posterior continuous curvilinear capsulorhexis and with anterior vitrectomy during 2-6 months after birth. Fourteen children (28 eyes) of age-sex matched with the aphalic group were selected as normal control group. CCT and intraocular pressure (IOP) were measured postoperatively and the results were compared between groups.
The mean CCT was 653.5±82.4μm in the aphakic group and 579.6±39.2μm in the control group, with a significant difference (P=0.000). The mean value of IOP in aphakic group (22.0±1.6mmHg) was greater than that of control group (16.9±2.1mmHg), P=0.023. There was a negative correlation between age and CCT in normal control group (r=-0.531, P=0.026), and there was no correlation in bilateral aphakia group (r=-0.324, P=0.165)
Aphakic children due to congenital cataract surgery have a greater CCT than normal children. It is necessary to consider CCT in evaluating IOP for children after congenital cataract surgery.
观察双侧先天性白内障手术患儿的中央角膜厚度（CCT）变化，并与从健康人群中选取的正常对照组进行比较。
一项横断面病例对照研究，纳入28例（56眼）因先天性白内障手术在出生后2至6个月行后囊连续环形撕囊联合前部玻璃体切除术的双侧无晶状体眼患儿（无晶状体眼组）。选取14名年龄和性别与无晶状体眼组匹配的儿童（28眼）作为正常对照组。术后测量CCT和眼压（IOP），并比较两组结果。
无晶状体眼组平均CCT为653.5±82.4μm，对照组为579.6±39.2μm，差异有统计学意义（P = 0.000）。无晶状体眼组平均IOP值（22.0±1.6mmHg）高于对照组（16.9±2.1mmHg），P = 0.023。正常对照组年龄与CCT呈负相关（r = -0.531，P = 0.026），双侧无晶状体眼组无相关性（r = -0.324，P = 0.165）。
先天性白内障手术所致无晶状体眼患儿的CCT高于正常儿童。在评估先天性白内障手术后儿童的IOP时，有必要考虑CCT。
