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[牡丹HPLC色谱指纹图谱的聚类分析]

[Clustering analysis of HPLC chromatographic fingerprints of Paeonia suffruticosa].

作者信息

Wu Mei-zhen, He Yan, Tang Li-ying, Wang Zhu-ju

机构信息

Sir Sun Sun Shaw Hospital, Medical College of Zhejiang University, Hangzhou 310016, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(11):1054-6.

Abstract

OBJECTIVE

To explore the utility of chromatographic data for quality control of Paeonia suffruticosa, a Chinese herbal medicine.

METHOD

Chromatographic fingerprints of Paeonia suffruticosa were determined by HPLC, the clustering analysis was used for data processing.

RESULT

The quantitative differences among different growing areas were found and could be used to classify herbals from different growing areas, while there seemed to be no quantitative differences for processing factor.

CONCLUSION

The method could be used in quality control for monitoring herbal quality control, and the result also suggested that different growing areas may greatly affected the herbal qualities.

摘要

目的

探讨色谱数据在中药牡丹皮质量控制中的应用。

方法

采用高效液相色谱法测定牡丹皮的色谱指纹图谱,并用聚类分析法进行数据处理。

结果

发现不同产地之间存在定量差异,可用于区分不同产地的药材,而加工因素似乎没有定量差异。

结论

该方法可用于质量控制以监测药材质量,结果还表明不同产地可能对药材质量有很大影响。

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