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[应用色谱指纹图谱建立虎掌南星炮制品质量标准的研究]

[Study on applying chromatographic fingerprints to establishing quality criterion of processed tuber of Pinellia pedatisecta].

作者信息

He Yan, Zhang Qi-wei, Zhang Yong-xin, Sun Jie, Wang Zhu-ju

机构信息

Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Being 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2004 Sep;29(9):874-6.

PMID:15575208
Abstract

OBJECTIVE

To explore the utility of principal component analysis (PCA) in conjunction with the window preprocessing scheme on chromatographic data for quality control.

METHOD

Chromatographic fingerprints of processed tuber of Pinellia pedatisecta were determined by HPLC, and the Window Preprocessing and PCA were used for data processing.

RESULT

The quantitative differences among different growing areas and different process batches were found with this method.

CONCLUSION

The method can be used in quality control for monitoring between-batch products of traditional Chinese pharmaceutical process.

摘要

目的

探讨主成分分析(PCA)结合窗口预处理方案在色谱数据质量控制中的应用。

方法

采用高效液相色谱法测定加工后的虎掌南星的色谱指纹图谱,并采用窗口预处理和主成分分析进行数据处理。

结果

该方法发现了不同种植区域和不同加工批次之间的定量差异。

结论

该方法可用于中药生产过程中间产品的质量控制监测。

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