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[白芍炮制品色谱指纹图谱的定量研究]

[Quantititive study for chromatographic fingerprints of processed products of Paeonia lactiflora].

作者信息

He Yan, Zhao Hui-dong, Tang Li-ying, Wang Zhu-ju, Zhang Qi-wei

机构信息

Institute of Basic Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(12):1161-4.

PMID:17802876
Abstract

OBJECTIVE

To explore the utility of Principal Factor Analysis (PFA) in chromatographic data for quality control.

METHOD

Chromatographic fingerprints of processed root pieces of Paeonia lactiflora were determined by HPLC, the PFA was used for data processing.

RESULT

The quantitative differences among different growing areas and different processing batches were found with the method.

CONCLUSION

The method could be used in quality control for monitoring between-batch products of traditional Chinese pharmaceutical process.

摘要

目的

探讨主因子分析(PFA)在色谱数据用于质量控制方面的效用。

方法

采用高效液相色谱法测定白芍饮片的色谱指纹图谱,并用主因子分析法进行数据处理。

结果

该方法发现了不同产地和不同加工批次之间的定量差异。

结论

该方法可用于中药生产过程中间产品批次间监测的质量控制。

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引用本文的文献

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Quick comparison of Radix Paeonia Alba, Radix Paeonia Rubra, and Cortex Moutan by high performance liquid chromatography coupled with monolithic columns and their chemical pattern recognition.高效液相色谱-整体柱法快速比较白芍、赤芍和牡丹皮及其化学模式识别
Pharmacogn Mag. 2012 Jul;8(31):237-43. doi: 10.4103/0973-1296.99290.