Kohrenhagen N, Eck M, Höller S, Dietl J
Department of Obstetrics and Gynecology, University of Wuerzburg, Josef-Schneider-Str. 4, 97080, Wuerzburg, Germany.
Arch Gynecol Obstet. 2008 Feb;277(2):175-8. doi: 10.1007/s00404-007-0427-0. Epub 2007 Aug 3.
Lymphoepithelioma-like carcinoma (LELC) is a rare variant of squamous cell carcinoma of the uterine cervix. In contrast to Asian women, Caucasian women have a low prevalence of cervical LELC with no infection of the Epstein-Barr virus (EBV) and sporadic appearances of human papilloma viruses (HPV) in Caucasian women.
We report a 36-year-old female Caucasian patient with LELC of the cervix.
In contrast to the present studies, our case of LELC of the cervix is not associated with EBV or high-risk HPV appearances.
This is the first study, that showed no relationship between LELC of the uterine cervix with EBV and high-risk HPV infections in a Caucasian woman.
淋巴上皮瘤样癌(LELC)是宫颈鳞状细胞癌的一种罕见变体。与亚洲女性不同,白种女性宫颈LELC的患病率较低,且白种女性中不存在爱泼斯坦-巴尔病毒(EBV)感染,人乳头瘤病毒(HPV)呈散发性出现。
我们报告一名36岁白种女性宫颈LELC患者。
与目前的研究不同,我们的宫颈LELC病例与EBV或高危HPV出现无关。
这是第一项表明白种女性宫颈LELC与EBV和高危HPV感染之间无关联的研究。