Kyozuka H, Watanabe T, Furukawa S, Soeda S, Kiko Y, Fujimori K
Eur J Gynaecol Oncol. 2017;38(3):459-461.
Lymphoepithelioma-like carcinoma (LELC) is a rare variant of carcinoma of the uterine cervix, of which Epstein-Barr virus (EBV) and/or human papilloma virus (HPV) may play an important role in the pathogenesis. The authors report a case of a patient with cervical LELC who was also examined for the presence of EBV and HPV. A 31-year-old Japanese female presented with irregular genital bleeding. The biopsy showed an invasive squamous cell carcinoma. Based on the clinical data, the patient was diagnosed as having squamous cervical carcinoma, and radical hysterectomy with ovarian conservation was performed. A diagnosis of cervical LELC was then made by histological methods. An additional examination revealed that the patient was infected with HPV types 16 and 71, but not infected with EBV.
淋巴上皮瘤样癌（LELC）是子宫颈癌的一种罕见变体，其中爱泼斯坦-巴尔病毒（EBV）和/或人乳头瘤病毒（HPV）可能在发病机制中起重要作用。作者报告了一例宫颈LELC患者，该患者也接受了EBV和HPV检测。一名31岁的日本女性出现不规则生殖器出血。活检显示为浸润性鳞状细胞癌。根据临床资料，该患者被诊断为宫颈鳞状癌，并进行了保留卵巢的根治性子宫切除术。随后通过组织学方法确诊为宫颈LELC。进一步检查发现该患者感染了16型和71型HPV，但未感染EBV。
