Department of Pathology, Krankenhaus Barmherzige Schwestern, Linz, Austria.
Diagn Pathol. 2011 Jan 10;6:4. doi: 10.1186/1746-1596-6-4.
This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy. Follow-up nine months later showed only slight vulvar atrophy, without signs of local recurrence or distant metastases.Although lymphoepithelioma-like carcinomas of the skin and the female genital tract are presumed to have a better prognosis than their counterparts in the upper aerodigestive tract, possibly due to earlier detection and therapy, this case documents their potential for early metastasis.
本报告描述了一例发生于 73 岁患者外阴的不典型 EBV 阴性淋巴上皮样癌。病变位于右侧小阴唇，通过部分外阴切除术进行切除。同步的前哨淋巴结活检显示右侧腹股沟区有单个微转移，随后进行局部放疗。9 个月后的随访仅显示轻微的外阴萎缩，无局部复发或远处转移的迹象。尽管皮肤和女性生殖道的淋巴上皮样癌的预后被认为优于上呼吸道的相应肿瘤，可能是因为更早的发现和治疗，但本病例证明了它们具有早期转移的潜力。
