Claudius C, Karacan H, Viby-Mogensen J
Department of Anaesthesia and Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
Br J Anaesth. 2007 Oct;99(4):514-7. doi: 10.1093/bja/aem213. Epub 2007 Aug 3.
It is often argued that neuromuscular monitoring is unnecessary when only one dose of an intermediate-acting neuromuscular blocking agent is given. This case report documents that it may take more than 3.5 h before it is possible to antagonize a block caused by a normal dose of rocuronium (0.6 mg kg(-1)). Possible causes of the extremely prolonged duration of action are discussed, as is the importance of quantitative neuromuscular monitoring.
人们常常认为，仅给予一剂中效神经肌肉阻滞剂时，神经肌肉监测并无必要。本病例报告证明，拮抗正常剂量罗库溴铵（0.6 mg·kg⁻¹）所致的阻滞可能需要超过3.5小时。文中讨论了作用时间极长的可能原因以及定量神经肌肉监测的重要性。
