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外科医生对一例长时间神经肌肉阻滞病例中神经肌肉拮抗不足的评估。

A surgeon's assessment of inadequate neuromuscular antagonism in a case of prolonged neuromuscular blockade.

作者信息

Lamberg James J, Answine Joseph F

机构信息

Department of Anesthesiology, Pennsylvania State University Milton S Hershey Medical Center, Pennsylvania, USA.

出版信息

J Anaesthesiol Clin Pharmacol. 2013 Apr;29(2):244-7. doi: 10.4103/0970-9185.111654.

DOI:10.4103/0970-9185.111654
PMID:23878451
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3713677/
Abstract

Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was given at the request of the surgical team. Possible causes of prolonged neuromuscular antagonism are discussed, as is the importance of neuromuscular assessment prior to the administration of additional neuromuscular blocking agents when receiving a surgeon request for additional neuromuscularblockade.

摘要

仅靠临床标准由外科医生评估神经肌肉阻滞程度是不可靠的。我们报告了一例持续5.5小时的延长神经肌肉阻滞病例,术中应手术团队要求额外给予了一剂神经肌肉松弛剂。文中讨论了神经肌肉拮抗延长的可能原因,以及在接到外科医生追加神经肌肉阻滞剂的请求时,在给予额外神经肌肉阻滞剂之前进行神经肌肉评估的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bc9/3713677/117faad92d61/JOACP-29-244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bc9/3713677/117faad92d61/JOACP-29-244-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bc9/3713677/117faad92d61/JOACP-29-244-g002.jpg

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Acta Anaesthesiol Scand. 2009 Aug;53(7):957-9. doi: 10.1111/j.1399-6576.2009.01977.x. Epub 2009 Apr 27.
2
Comparison of the adductor pollicis, orbicularis oculi, and corrugator supercilii as indicators of adequacy of muscle relaxation for tracheal intubation.比较拇收肌、眼轮匝肌和皱眉肌作为气管插管肌肉松弛是否充分的指标。
Br J Anaesth. 2009 Jun;102(6):869-74. doi: 10.1093/bja/aep064. Epub 2009 Apr 17.
3
Prolonged residual paralysis after a single intubating dose of rocuronium.
单次插管剂量的罗库溴铵后出现长时间残余麻痹。
Br J Anaesth. 2007 Oct;99(4):514-7. doi: 10.1093/bja/aem213. Epub 2007 Aug 3.
4
TOF count at corrugator supercilii reflects abdominal muscles relaxation better than at adductor pollicis.皱眉肌处的颤搐计数比拇内收肌处更能反映腹部肌肉的放松情况。
Br J Anaesth. 2007 May;98(5):611-4. doi: 10.1093/bja/aem048. Epub 2007 Mar 23.
5
Pharmacokinetics and pharmacodynamics of rocuronium in patients with and without renal failure.罗库溴铵在有和无肾衰竭患者中的药代动力学和药效学。
Eur J Anaesthesiol. 2005 Jan;22(1):4-10. doi: 10.1017/s0265021505000025.
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Variability of duration of action of neuromuscular-blocking drugs in elderly patients.老年患者中神经肌肉阻滞药物作用持续时间的变异性。
Acta Anaesthesiol Scand. 2005 Mar;49(3):312-5. doi: 10.1111/j.1399-6576.2005.00634.x.
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