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急性额窦炎的并发症:一项回顾性研究。

Complications of acute frontal sinusitis: a retrospective study.

作者信息

Betz Christian S, Issing Wolfgang, Matschke Johannes, Kremer Anne, Uhl Eberhard, Leunig Andreas

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University, Munich, Germany.

出版信息

Eur Arch Otorhinolaryngol. 2008 Jan;265(1):63-72. doi: 10.1007/s00405-007-0411-0. Epub 2007 Aug 4.

DOI:10.1007/s00405-007-0411-0
PMID:17676328
Abstract

Even though being a rare condition in the era of antibiotic treatment, complications of acute frontal sinusitis still pose a potentially life-threatening problem. We present a clinical case series using a combined surgical approach. Within a 7 year period, all patients with a suppurative complication of an acute frontal sinusitis were included into this retrospective study and evaluated concerning histories, diagnostic and therapeutic procedures and achieved outcomes. Twelve patients (11-74 years) were identified; this corresponds to 0.3% of all patients that have undergone paranasal sinus surgery and 15.4% of all patients with infectious complications of sinusitis. The cases could be subdivided as follows: intracranial complications (4/12), osteomyelitis of the frontal bone (4/12), frontal/orbital soft tissue involvement (3/12) and endoluminal empyema (1/12). These were all correctly diagnosed by CT and (especially in the cases of intracranial complications) MRI. The microbiological spectrum comprised mostly non-multiresistant Staphylococci and Streptococci. All patients received aggressive antibiotic and combined surgical treatment. Within a mean follow up period of 32 months, the disease-related mortality and the rate of severe long-term ailment was 0%. If detected and treated early, both long-term morbidity and mortality can be minimised. A close cooperation with the related specialties (neurosurgery, ophthalmology, radiology) is thereby of utmost importance.

摘要

尽管在抗生素治疗时代急性额窦炎并发症较为罕见,但它仍然是一个潜在的危及生命的问题。我们展示了一组采用联合手术方法的临床病例。在7年期间,所有患有急性额窦炎化脓性并发症的患者都被纳入这项回顾性研究,并对病史、诊断和治疗程序以及治疗结果进行了评估。确定了12名患者(年龄11 - 74岁);这相当于所有接受鼻窦手术患者的0.3%以及所有患有鼻窦炎感染性并发症患者的15.4%。病例可细分为以下几类:颅内并发症(4/12)、额骨骨髓炎(4/12)、额部/眶部软组织受累(3/12)和腔内积脓(1/12)。这些均通过CT(尤其是颅内并发症病例)和MRI正确诊断。微生物谱主要包括非多重耐药葡萄球菌和链球菌。所有患者均接受了积极的抗生素和联合手术治疗。在平均32个月的随访期内,疾病相关死亡率和严重长期疾病发生率为0%。如果早期发现并治疗,长期发病率和死亡率均可降至最低。因此,与相关专科(神经外科、眼科、放射科)密切合作至关重要。

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Antibiotic use and serious complications following acute otitis media and acute sinusitis: a retrospective cohort study.抗生素使用与急性中耳炎和急性鼻窦炎后的严重并发症:一项回顾性队列研究。
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The prevalence of intracranial complications in pediatric frontal sinusitis.小儿额窦炎颅内并发症的患病率。
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