Betz Christian S, Issing Wolfgang, Matschke Johannes, Kremer Anne, Uhl Eberhard, Leunig Andreas
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University, Munich, Germany.
Eur Arch Otorhinolaryngol. 2008 Jan;265(1):63-72. doi: 10.1007/s00405-007-0411-0. Epub 2007 Aug 4.
Even though being a rare condition in the era of antibiotic treatment, complications of acute frontal sinusitis still pose a potentially life-threatening problem. We present a clinical case series using a combined surgical approach. Within a 7 year period, all patients with a suppurative complication of an acute frontal sinusitis were included into this retrospective study and evaluated concerning histories, diagnostic and therapeutic procedures and achieved outcomes. Twelve patients (11-74 years) were identified; this corresponds to 0.3% of all patients that have undergone paranasal sinus surgery and 15.4% of all patients with infectious complications of sinusitis. The cases could be subdivided as follows: intracranial complications (4/12), osteomyelitis of the frontal bone (4/12), frontal/orbital soft tissue involvement (3/12) and endoluminal empyema (1/12). These were all correctly diagnosed by CT and (especially in the cases of intracranial complications) MRI. The microbiological spectrum comprised mostly non-multiresistant Staphylococci and Streptococci. All patients received aggressive antibiotic and combined surgical treatment. Within a mean follow up period of 32 months, the disease-related mortality and the rate of severe long-term ailment was 0%. If detected and treated early, both long-term morbidity and mortality can be minimised. A close cooperation with the related specialties (neurosurgery, ophthalmology, radiology) is thereby of utmost importance.
尽管在抗生素治疗时代急性额窦炎并发症较为罕见,但它仍然是一个潜在的危及生命的问题。我们展示了一组采用联合手术方法的临床病例。在7年期间,所有患有急性额窦炎化脓性并发症的患者都被纳入这项回顾性研究,并对病史、诊断和治疗程序以及治疗结果进行了评估。确定了12名患者(年龄11 - 74岁);这相当于所有接受鼻窦手术患者的0.3%以及所有患有鼻窦炎感染性并发症患者的15.4%。病例可细分为以下几类:颅内并发症(4/12)、额骨骨髓炎(4/12)、额部/眶部软组织受累(3/12)和腔内积脓(1/12)。这些均通过CT(尤其是颅内并发症病例)和MRI正确诊断。微生物谱主要包括非多重耐药葡萄球菌和链球菌。所有患者均接受了积极的抗生素和联合手术治疗。在平均32个月的随访期内,疾病相关死亡率和严重长期疾病发生率为0%。如果早期发现并治疗,长期发病率和死亡率均可降至最低。因此,与相关专科(神经外科、眼科、放射科)密切合作至关重要。