Radhika Ganesan, Sudha Vasudevan, Mohan Sathya Rangaswamy, Ganesan Anbazhagan, Mohan Viswanathan
Madras Diabetes Research Foundation and Dr Mohan's Diabetes Specialities Centre, 4 Conran Smith Road, Gopalapuram, Chennai, India.
Br J Nutr. 2008 Feb;99(2):398-405. doi: 10.1017/S0007114507803965. Epub 2007 Aug 3.
The study examines the relationship between fruit and vegetable intake (g/d) and CVD risk factors in urban south Indians. The study population comprised of 983 individuals aged > or = 20 years selected from the Chennai Urban Rural Epidemiological Study (CURES), a population-based cross-sectional study on a representative population of Chennai in southern India. Fruit and vegetable intake (g/d) was measured using a validated semi-quantitative FFQ. Linear regression analysis revealed that after adjusting for potential confounders such as age, sex, smoking, alcohol, BMI and total energy intake, the highest quartile of fruit and vegetable intake (g/d) showed a significant inverse association with systolic blood pressure (beta = - 2.6 (95 % CI - 5.92, - 1.02) mmHg; P = 0.027), BMI (beta = - 2.3 (95 % CI - 2.96, - 1.57) kg/m2; P < 0.0001), waist circumference (beta = - 2.6 (95 % CI - 3.69, - 1.46) cm; P < 0.0001), total cholesterol (beta = - 50 (95 % CI - 113.9, - 13.6) mg/l; P = 0.017) and LDL-cholesterol concentration (beta = - 55 (95 % CI - 110.8, - 11.1) mg/l; P = 0.039) when compared with the lowest quartile. A higher intake of fruit and vegetables explained 48 % of the protective effect against CVD risk factors. Increased intake of fruits and vegetables could play a protective role against CVD in Asian Indians who have high rates of premature coronary artery disease.
该研究调查了印度南部城市居民的水果和蔬菜摄入量（克/天）与心血管疾病风险因素之间的关系。研究人群包括从钦奈城乡流行病学研究（CURES）中选取的983名年龄≥20岁的个体，CURES是一项针对印度南部钦奈代表性人群的基于人群的横断面研究。水果和蔬菜摄入量（克/天）通过经过验证的半定量食物频率问卷进行测量。线性回归分析显示，在调整年龄、性别、吸烟、饮酒、体重指数和总能量摄入等潜在混杂因素后，与最低四分位数相比，水果和蔬菜摄入量（克/天）的最高四分位数与收缩压（β=-2.6（95%CI-5.92，-1.02）mmHg；P=0.027）、体重指数（β=-2.3（95%CI-2.96，-1.57）kg/m2；P<0.0001）、腰围（β=-2.6（95%CI-3.69，-1.46）cm；P<0.0001）、总胆固醇（β=-50（95%CI-113.9，-13.6）mg/l；P=0.017）和低密度脂蛋白胆固醇浓度（β=-55（95%CI-110.8，-11.1）mg/l；P=0.039）呈显著负相关。较高的水果和蔬菜摄入量解释了对心血管疾病风险因素48%的保护作用。增加水果和蔬菜的摄入量可能对早发性冠状动脉疾病发生率较高的亚洲印度人预防心血管疾病起到保护作用。
