Hirode Grishma, Vittinghoff Eric, Bharmal Nazleen H, Kandula Namratha R, Kanaya Alka M
OakCare Medical Group, Highland Hospital, 1411 E 31st St, Oakland, CA, 94602, USA.
UCSF Department of Epidemiology and Biostatistics, 550 16th St, San Francisco, CA, 94158, USA.
BMC Cardiovasc Disord. 2019 Mar 29;19(1):75. doi: 10.1186/s12872-019-1045-z.
South Asians have disproportionately high rates of cardiovascular disease. Dyslipidemia, a contributing factor, may be influenced by lifestyle, which can vary by religious beliefs. Little is known about South Asian religions and associations with dyslipidemia.
Cross-sectional analyses of the MASALA study (n = 889). We examined the associations between religious affiliation and cholesterol levels using multivariate linear regression models. We determined whether smoking, alcohol use, physical activity, and dietary pattern mediated these associations.
Mean LDL was 112 ± 32 mg/dL, median HDL was 48 mg/dL (IQR:40-57), and median triglycerides was 118 mg/dL (IQR:88-157). Muslims had higher LDL and triglycerides, and lower HDL, while participants with no religious affiliation had lower LDL and higher HDL. The difference in HDL between Muslims and those with no religious affiliation was partly explained by alcohol consumption.
Religion-specific tailoring of interventions designed to promote healthy lifestyle to reduce cholesterol among South Asians may be useful.
南亚人心血管疾病发病率极高。血脂异常是一个促成因素，可能受生活方式影响，而生活方式会因宗教信仰不同而有所差异。关于南亚宗教及其与血脂异常的关联，人们知之甚少。
对 MASALA 研究（n = 889）进行横断面分析。我们使用多元线性回归模型研究宗教归属与胆固醇水平之间的关联。我们确定吸烟、饮酒、身体活动和饮食模式是否介导了这些关联。
低密度脂蛋白（LDL）均值为 112 ± 32 mg/dL，高密度脂蛋白（HDL）中位数为 48 mg/dL（四分位间距：40 - 57），甘油三酯中位数为 118 mg/dL（四分位间距：88 - 157）。穆斯林的 LDL 和甘油三酯水平较高，HDL 水平较低，而无宗教归属的参与者 LDL 水平较低，HDL 水平较高。穆斯林与无宗教归属者之间 HDL 的差异部分可由饮酒来解释。
针对南亚人量身定制旨在促进健康生活方式以降低胆固醇的干预措施，按宗教信仰区分可能会有帮助。
