Ahmed Hashim Uddin, Arya Manit, Levitt Gill, Duffy Patrick G, Mushtaq Imran, Sebire Neil J
Institute of Urology and Nephrology, University College London Hospitals NHS Foundation Trust, London, UK.
Lancet Oncol. 2007 Aug;8(8):730-7. doi: 10.1016/S1470-2045(07)70241-3.
Non-Wilms' tumours form a small heterogeneous group of clinically significant renal malignancies in children, including renal-cell carcinoma, clear-cell sarcoma, (congenital) mesoblastic nephroma, rhabdoid tumour, and renal medullary carcinoma. Good progress has been made in the assessment of these tumours, which has led to a greater understanding of the molecular changes that occur in their development. This review is the first of two parts, and provides an updated review of the clinical presentation, imaging, and pathology of these tumours.
非威尔姆斯瘤是儿童中一组临床意义重大的肾脏恶性肿瘤，种类较少且具有异质性，包括肾细胞癌、透明细胞肉瘤、（先天性）中胚叶肾瘤、横纹肌样瘤和肾髓质癌。在这些肿瘤的评估方面已取得了良好进展，这使人们对其发生发展过程中出现的分子变化有了更深入的了解。本综述是分为两部分的系列综述中的第一篇，对这些肿瘤的临床表现、影像学和病理学进行了最新综述。
