Van den Berg A A, Prabhu N V
Department of Anaesthesia, Riyadh Armed Forces Hospital, Kingdom of Saudi Arabia.
Anaesth Intensive Care. 1995 Apr;23(2):165-7. doi: 10.1177/0310057X9502300207.
Two hundred and seventy-eight patients scheduled for all types of surgery and premedicated with diazepam and metoclopramide were randomly allocated to one of four groups to compare the relative pain of an injection of 0.25 ml of lignocaine 1% via a 25 gauge needle with the pain of the siting of a 21 gauge Butterfly (Abbott), 23 gauge Butterfly or a 20 gauge Venflon (Vigo Spectramed). The injection of lignocaine and insertion of the 23 gauge Butterfly were associated with the least complaints of pain and least observed responses to pain. The 21 gauge Butterfly and 20 gauge Venflon were associated with complaints of greater pain and more pain responses. We conclude that a pre-cannulation injection of lignocaine causes minimal discomfort and is the most appropriate means of reducing the discomfort of venous cannulation when not using skin penetrating analgesic creams.
278例计划接受各类手术且已用安定和胃复安进行术前用药的患者被随机分为四组，以比较用25号针头注射0.25毫升1%利多卡因的疼痛程度与使用21号蝶形针（雅培公司）、23号蝶形针或20号静脉留置针（威高施美德公司）穿刺时的疼痛程度。注射利多卡因和使用23号蝶形针穿刺时患者抱怨的疼痛最少，观察到的疼痛反应也最少。21号蝶形针和20号静脉留置针穿刺时患者抱怨的疼痛更多，疼痛反应也更多。我们得出结论，在不使用皮肤渗透镇痛乳膏的情况下，预先注射利多卡因导致的不适最小，是减轻静脉穿刺不适的最合适方法。
