Mitsuoka Masahiro, Sakuragi Tohru, Itoh Tsuyoshi
Department of Thoracic and Cardiovascular Surgery, Saga University Faculty of Medicine, 5-1-1 Nabeshima, Saga 849-8501, Japan.
Gen Thorac Cardiovasc Surg. 2007 Jul;55(7):275-80. doi: 10.1007/s11748-007-0131-9.
The purpose of this study was to evaluate the clinical benefits and complications of Dumon stent insertion for patients with central airway disorders including stenosis and fistula.
This was a retrospective analysis of medical records regarding alleviation of symptoms, occurrence of complications, and technical problems. Since August 1998, the Dumon stent has been used in 35 consecutive patients, included 24 with malignant airway stenosis, 5 with benign stenosis, and 6 with airway fistula. Altogether, 7 patients had a straight stent inserted into the trachea, 17 had a Y-stent inserted into the carina, and 11 patients had a straight stent inserted into the bronchus.
In 33 of the 35 patients, the symptoms dramatically diminished after stent insertion. Poststenting complications included increased coughing in 37% of the patients, an obstruction of the stent due to secretion in 8.6%, migration in 5.7%, granulation in 2.9%, and cerebral infarction in 2.9%. Ten patients had the stent removed for various reasons, and five of the ten underwent reinsertion of a new stent. Migration could be avoided by external fixation with nylon threads in the upper trachea. Three of six patients with an airway fistula showed resolution of the fistula, and the remaining three patients improved symptomatically. Five of these six patients had undergone radiotherapy prior to stent insertion.
The Dumon stent was found to be effective for treating not only airway stenosis but also airway fistula, with permissible complications. The Dumon stent is therefore considered to be the most effective airway stent presently available worldwide based on both cost and safety factors.
本研究旨在评估 Dumon 支架置入术对包括狭窄和瘘管在内的中央气道疾病患者的临床益处及并发症。
这是一项对有关症状缓解、并发症发生情况及技术问题的病历进行的回顾性分析。自 1998 年 8 月以来,连续 35 例患者使用了 Dumon 支架,其中 24 例为恶性气道狭窄,5 例为良性狭窄,6 例为气道瘘管。共有 7 例患者在气管内插入直管状支架,17 例在隆突处插入 Y 形支架,11 例在支气管内插入直管状支架。
35 例患者中有 33 例在支架置入后症状显著减轻。支架置入后的并发症包括 37%的患者咳嗽加重、8.6%的患者因分泌物导致支架阻塞、5.7%的患者支架移位、2.9%的患者出现肉芽组织增生以及 2.9%的患者发生脑梗死。10 例患者因各种原因取出支架,其中 5 例再次置入新支架。通过在上段气管用尼龙线进行外部固定可避免支架移位。6 例气道瘘管患者中有 3 例瘘管闭合,其余 3 例症状改善。这 6 例患者中有 5 例在支架置入前接受过放疗。
发现 Dumon 支架不仅对气道狭窄有效,对气道瘘管也有效,且并发症在可接受范围内。因此,基于成本和安全因素,Dumon 支架被认为是目前全球最有效的气道支架。