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使用脱细胞猪膀胱基质成功地对既往荚膜组织胞浆菌感染所致的不愈合气管食管瘘进行支气管内治疗。

Successful endobronchial treatment of a non-healing tracheoesophageal fistula from a previous histoplasmosis capsulatum infection using decellularized porcine urinary bladder matrix.

作者信息

Mahajan Amit K, Newkirk Mia, Rosner Carolyn, Khandhar Sandeep J

机构信息

Inova Fairfax Hospital, Inova Heart and Vascular Institute, Inova Fairfax Hospital, Falls Church, VA.

Dartmouth College, Hanover, NH, USA.

出版信息

J Surg Case Rep. 2018 Aug 13;2018(8):rjy187. doi: 10.1093/jscr/rjy187. eCollection 2018 Aug.

Abstract

Tracheoesophageal fistulas (TEF) are pathologic communications between the esophagus and the trachea or bronchi. The development of a TEF can result from malignant or benign etiologies. A common approach for the treatment of TEFs is the placement of endobronchial and esophageal stents to facilitate healing of the communication. This case report describes the successful treatment of a TEF resulting from calcified mediastinal lymphadenopathy due to a previous Histoplasmosis capsulatum infection. In addition to placement of endobronchial and esophageal stents, the non-healing TEF was treated with ACell (Gentrix) decellularized porcine urinary bladder matrix to facilitate complete closure of the fistulous tract.

摘要

气管食管瘘(TEF)是食管与气管或支气管之间的病理性通道。TEF的形成可由恶性或良性病因引起。治疗TEF的常用方法是放置支气管内支架和食管支架,以促进通道愈合。本病例报告描述了一例因既往荚膜组织胞浆菌感染导致钙化纵隔淋巴结病引起的TEF的成功治疗。除了放置支气管内支架和食管支架外,还使用ACell(Gentrix)脱细胞猪膀胱基质治疗未愈合的TEF,以促进瘘管完全闭合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ec1/6101604/b6df5394ddbe/rjy187f01.jpg

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