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使用杜蒙Y型支架治疗累及隆突的恶性疾病:86例患者的回顾性研究

Use of the Dumon Y-stent in the management of malignant disease involving the carina: a retrospective review of 86 patients.

作者信息

Dutau Hervé, Toutblanc Bénédicte, Lamb Carla, Seijo Luis

机构信息

Thoracic Endoscopy Center, Hôpital Sainte Marguerite, 270 Blvd de Sainte Marguerite, 13009 Marseille, France.

出版信息

Chest. 2004 Sep;126(3):951-8. doi: 10.1378/chest.126.3.951.

DOI:10.1378/chest.126.3.951
PMID:15364778
Abstract

OBJECTIVE

To study the efficacy of symptom relief and the safety of the Dumon Y-stent for central airway obstruction in malignant main carinal involvement and in malignant tracheoesophageal fistulas.

DESIGN

A retrospective review.

SETTING

Thoracic endoscopy referral center.

PATIENTS AND METHODS

The medical records of 86 patients who had undergone the placement of a Dumon Y-stent at our institution were reviewed and analyzed.

RESULTS

Ninety Dumon Y-stents were placed in 86 patients to relieve symptoms of dyspnea, cough, and/or hemoptysis. Four of these patients required removal of that stent and replacement with a longer Dumon Y-stent due to tumor progression. There were only two instances of procedure-related adverse effects, which included coughing following stent placement lasting 1 week in one patient and stent migration in another patient. In the case of stent migration, the stent required immediate removal, and the patient experienced no adverse consequences. The remaining patients tolerated the stent well, and all experienced subjective symptomatic relief. There were no stent-related deaths. The average duration of a stent after placement was 133 days. The median time of survival following stent insertion was 181 days. Forty-five percent of all patients died at 3 months, and 72% died at 6 months.

CONCLUSION

The Dumon Y-stent proved to be useful and was well-tolerated in the management of malignant disease involving the main carina. It also provided successful palliation in patients with malignant tracheoesophageal fistulas.

摘要

目的

研究杜蒙Y形支架对恶性主支气管隆突受累及恶性气管食管瘘所致中央气道阻塞的症状缓解疗效及安全性。

设计

回顾性研究。

地点

胸科内镜转诊中心。

患者和方法

回顾并分析了在本机构接受杜蒙Y形支架置入术的86例患者的病历。

结果

86例患者共置入90枚杜蒙Y形支架以缓解呼吸困难、咳嗽和/或咯血症状。其中4例患者因肿瘤进展需要取出该支架并更换更长的杜蒙Y形支架。仅发生2例与手术相关的不良反应,1例患者支架置入后咳嗽持续1周,另1例患者支架移位。对于支架移位的情况,需要立即取出支架,患者未出现不良后果。其余患者对支架耐受性良好,均主观症状缓解。无支架相关死亡病例。支架置入后的平均持续时间为133天。支架置入后的中位生存时间为181天。所有患者中45%在3个月时死亡,72%在6个月时死亡。

结论

杜蒙Y形支架在治疗累及主支气管隆突的恶性疾病中被证明是有用的且耐受性良好。它也为恶性气管食管瘘患者提供了成功的姑息治疗。

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