Murray Greg, Goldstone Eliot, Cunningham Everarda
Faculty of Life and Social Sciences, Swinburne University of Technology, Hawthorn, Victoria, Australia.
Bipolar Disord. 2007 Aug;9(5):453-61. doi: 10.1111/j.1399-5618.2007.00456.x.
The aim of this study was to model normal personality correlates of the predisposition(s) to bipolar disorder (BD), and in so doing explore the proposition that the tendency to bipolar depression [trait depression (T-Depression)] and the tendency to mania [trait mania (T-Mania)] can usefully be viewed as separable but correlated dimensions of BD predisposition.
A well student sample (n = 176, modal age 18-25 years, 71% female) completed the NEO Personality Inventory-Revised and the General Behavior Inventory.
A good-fitting model (normed chi2 = 0.60, significance of chi2 = 0.73) was identified in which T-Depression was determined solely by neuroticism, while T-Mania was determined by extraversion and (negative) agreeableness. The pathway from T-Depression to T-Mania was also significant (standardized regression weight = 0.80), with a weaker significant reciprocal path (coefficient = 0.27). A model in which bipolar vulnerability was represented as a single dimension (T-Bipolarity) also provided a good fit to the data, but provided less heuristic power.
Predisposition to BD can be usefully understood in terms of two reciprocally related dimensions of vulnerability (T-Depression and T-Mania), which can be separated on the basis of their personality correlates.
本研究旨在构建双相情感障碍（BD）易感性的正常人格关联模型，并借此探讨双相抑郁倾向[特质抑郁（T - 抑郁）]和躁狂倾向[特质躁狂（T - 躁狂）]可被视为BD易感性中可分离但相关的维度这一命题。
一个健康的学生样本（n = 176，众数年龄18 - 25岁，71%为女性）完成了大五人格量表修订版（NEO Personality Inventory - Revised）和一般行为量表（General Behavior Inventory）。
确定了一个拟合良好的模型（标准化卡方值 = 0.60，卡方显著性 = 0.73），其中T - 抑郁仅由神经质决定，而T - 躁狂由外向性和（负性）宜人性决定。从T - 抑郁到T - 躁狂的路径也具有显著性（标准化回归权重 = 0.80），反向路径较弱但也具有显著性（系数 = 0.27）。一个将双相易感性表示为单一维度（T - 双相性）的模型也能很好地拟合数据，但启发性较低。
BD易感性可以从两个相互关联的易感性维度（T - 抑郁和T - 躁狂）来有效理解，这两个维度可以根据其人格关联进行区分。
