Anavekar Namrata S, Williams Richard, Chong Alvin H
Department of Medicine (Dermatology), St Vincent's Hospital, 41 Victoria Parade, Fitzroy, Melbourne, VIC 3065, Australia.
Australas J Dermatol. 2007 Aug;48(3):161-4. doi: 10.1111/j.1440-0960.2007.00371.x.
A retrospective analysis was performed of patients meeting the clinicopathological diagnosis of Sweet's syndrome identified over a 10-year period, in a metropolitan hospital. Nine patients met the inclusion criteria. Two patients had preceding streptococcal infection, two had associated inflammatory bowel disease, two had idiopathic Sweet's syndrome, and three had an underlying malignancy, one of whom was receiving granulocyte colony-stimulating factor. Although only three patients were found to have an elevated white cell count, erythrocyte sedimentation rate or C-reactive protein was elevated in all patients when measured. There was a wide spectrum of clinical presentations, with variations in lesion distribution and the presence/absence of systemic symptoms such as fever and arthralgia. Fever was observed in two-thirds of cases. Seven patients responded to oral corticosteroids, while one patient cleared spontaneously and one patient was lost to follow up. As erythrocyte sedimentation rate or C-reactive protein was elevated in all cases when measured, it may be a useful diagnostic tool.
对一家大都市医院在10年期间确诊为Sweet综合征的患者进行了回顾性分析。9名患者符合纳入标准。2名患者先前有链球菌感染，2名患者伴有炎症性肠病，2名患者患有特发性Sweet综合征，3名患者有潜在恶性肿瘤，其中1名正在接受粒细胞集落刺激因子治疗。虽然仅3名患者白细胞计数升高，但所有患者的红细胞沉降率或C反应蛋白检测时均升高。临床表现多种多样，病变分布以及是否存在发热和关节痛等全身症状存在差异。三分之二的病例观察到发热。7名患者对口服皮质类固醇有反应，1名患者自行缓解，1名患者失访。由于所有病例检测时红细胞沉降率或C反应蛋白均升高，它可能是一种有用的诊断工具。
