Kalouche Hassan, Watson Alan, Routley Douglas
Department of Dermatology, John Hunter Hospital, Newcastle, New South Wales, Australia.
Australas J Dermatol. 2007 Aug;48(3):182-4. doi: 10.1111/j.1440-0960.2007.00376.x.
A 42-year-old woman presented with blue lunulae in association with argyria and hypercopprecaemia. The argyria was caused by the regular ingestion of colloidal silver in water over an extended period of time. The raised copper may have contributed to the nail discolouration, and was believed to be due either to ingestion of copper-containing multivitamin tablets or as an acute-phase reactant. We believe that the ease of access to, and lack of stringent regulatory controls over, food supplements and alternative medicines may cause similar cases in the future. We therefore recommend that all patients should be routinely questioned on their use of over-the-counter preparations and alternative medicines.
一名42岁女性因银质沉着症和高铜血症出现蓝色甲半月。银质沉着症是长期定期饮用含胶体银的水所致。铜含量升高可能导致指甲变色，据信这要么是由于摄入含铜的多种维生素片，要么是作为急性期反应物。我们认为，食品补充剂和替代药物易于获取且缺乏严格监管，未来可能会导致类似病例。因此，我们建议对所有患者常规询问其非处方制剂和替代药物的使用情况。
