Chevalley Thierry, Guilley Edith, Herrmann François R, Hoffmeyer Pierre, Rapin Charles-Henri, Rizzoli René
Service des maladies osseuses, Centre collaborateur de I'OMS pour la prévention de l'ostéoporose, Département de réhabilitation et gériatrie, HUG, Genève.
Rev Med Suisse. 2007 Jun 13;3(115):1528-30, 1532-3.
Hip fractures are a major cause of burden associated with osteoporosis in terms of mortality, disability, and costs. Many studies reveal an increase of the age-adjusted hip fracture incidence but long-term data on secular changes in women and men within a well-defined community are still rare. From 1991 to 2000, 4115 hip fractures were recorded in Geneva in 2981 women and 822 men 50 years and older. Over this 10-year period, the age-adjusted incidence of hip fractures, standardized to the 2000 Geneva population, decreased significantly by 1.4%/year in women (p = 0.021), but remained stable in men (+0.5%/year, p = 0.66), suggesting a reversal of the previously observed secular trend.
就死亡率、残疾率和成本而言,髋部骨折是与骨质疏松症相关的主要负担来源。许多研究表明,年龄调整后的髋部骨折发病率有所上升,但在一个明确界定的社区内,关于女性和男性长期变化的长期数据仍然很少。1991年至2000年期间,日内瓦记录了2981名50岁及以上女性和822名男性的4115例髋部骨折。在这10年期间,根据2000年日内瓦人口标准化的年龄调整后髋部骨折发病率,女性每年显著下降1.4%(p = 0.021),而男性则保持稳定(每年+0.5%,p = 0.66),这表明之前观察到的长期趋势出现了逆转。