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以色列南部女性和男性骨质疏松性髋部骨折的发病率呈显著的长期上升趋势。

Marked secular increase in the incidence rates of osteoporotic hip fractures in women and men in southern Israel.

作者信息

Liel Yair, Castel Hana, Alkalay Daphna

机构信息

Endocrine Unit, Dept of Medicine C, Soroka University Hospital, Beer Sheva, Israel.

出版信息

Isr Med Assoc J. 2005 Nov;7(11):708-11.

PMID:16308993
Abstract

BACKGROUND

For the last 35 years, our medical center has been the only referral center and provider of emergency medical services for a well-defined geographic area in southern Israel.

OBJECTIVES

To evaluate trends in the incidence of hip fractures in this population.

METHODS

The study was based on two surveys done approximately 20 years apart. It included women and men 50 years and older with radiographic evidence of a new hip fracture caused by low impact trauma. Only fractures that resulted from low or moderate trauma were considered for the current study. Incidence rates were calculated based on population data obtained from the official Central Bureau of Statistics.

RESULTS

There was an overall twofold increase in the incidence rate of hip fractures. However, this increase occurred almost exclusively in the over-75 year old age groups (2.5-fold increase, both in women and men). The mean (and median) age of patients with hip fractures increased significantly over the study period, corresponding to the increase in longevity between the two periods.

CONCLUSIONS

There was a marked secular increase in the incidence of proximal hip fractures in both genders, primarily because of an increase in the fracture rate in the very old. The increase in median age of fracture patients suggests that the observed increase in fracture rate can be attributed mainly to aging of the population rather than to deterioration in bone quality over the generations.

摘要

背景

在过去35年里,我们的医疗中心一直是以色列南部一个明确地理区域内唯一的转诊中心和紧急医疗服务提供者。

目的

评估该人群髋部骨折发病率的趋势。

方法

该研究基于相隔约20年进行的两项调查。研究对象包括50岁及以上有因低冲击力创伤导致新髋部骨折影像学证据的女性和男性。本研究仅考虑由低或中度创伤导致的骨折。发病率是根据从官方中央统计局获得的人口数据计算得出的。

结果

髋部骨折发病率总体上升了两倍。然而,这种上升几乎完全发生在75岁以上年龄组(女性和男性均增加了2.5倍)。在研究期间,髋部骨折患者的平均(和中位)年龄显著增加,这与两个时期之间预期寿命的增加相对应。

结论

两性近端髋部骨折发病率均出现明显的长期上升,主要原因是高龄人群骨折率增加。骨折患者中位年龄的增加表明,观察到的骨折率上升主要可归因于人口老龄化,而非几代人以来骨质的恶化。

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