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癌症患者失眠与生活质量满意度之间的关系。

The relationship between insomnia and patient satisfaction with quality of life in cancer.

作者信息

Lis Christopher G, Gupta Digant, Grutsch James F

机构信息

Office of Research, Cancer Treatment Centers of America (CTCA), Midwestern Regional Medical Center, Zion, IL 60099, USA.

出版信息

Support Care Cancer. 2008 Mar;16(3):261-6. doi: 10.1007/s00520-007-0314-z. Epub 2007 Aug 8.

Abstract

GOALS OF WORK

Insomnia is the most common sleep disorder in patients with advanced cancer. The goal of this study was to investigate the relationship between insomnia and patient satisfaction with quality of life (QoL) in cancer.

MATERIALS AND METHODS

A case series of 954 cancer patients treated at Cancer Treatment Centers of America was investigated. Insomnia was measured using the EORTC QLQ-C30 insomnia subscale. Patient satisfaction with QoL was measured using the Ferrans and Powers Quality of Life Index (QLI). The relationship between insomnia and QLI was evaluated using multivariate analysis of variance and multiple regression analysis.

RESULTS

Of 954 patients, 579 were females and 375 males, with the median age at presentation of 56 years (range, 20-90 years). Most common cancers were breast (26%), colorectal (19%), and lung (16%). After controlling for the effects of age and treatment history, every 10-unit increase in insomnia was statistically significantly associated with 0.67-, 0.17-, 0.42-, 0.20-, and 0.42-unit decline in QLI health/physical, social/economic, psychological/spiritual, family, and overall QoL functioning, respectively.

CONCLUSIONS

We found that insomnia is strongly correlated with patient satisfaction with QoL in cancer. Future studies should evaluate the impact of integrative cancer care services on patient satisfaction with QoL.

摘要

工作目标

失眠是晚期癌症患者中最常见的睡眠障碍。本研究的目的是调查失眠与癌症患者生活质量(QoL)满意度之间的关系。

材料与方法

对在美国癌症治疗中心接受治疗的954例癌症患者进行了病例系列研究。使用欧洲癌症研究与治疗组织(EORTC)QLQ-C30失眠子量表测量失眠情况。使用费兰斯和鲍尔斯生活质量指数(QLI)测量患者对生活质量的满意度。使用多因素方差分析和多元回归分析评估失眠与QLI之间的关系。

结果

954例患者中,579例为女性,375例为男性,就诊时的中位年龄为56岁(范围20-90岁)。最常见的癌症是乳腺癌(26%)、结直肠癌(19%)和肺癌(16%)。在控制年龄和治疗史的影响后,失眠每增加10个单位,QLI健康/身体、社会/经济、心理/精神、家庭和总体生活质量功能分别在统计学上显著下降0.67、0.17、0.42、0.20和0.42个单位。

结论

我们发现失眠与癌症患者生活质量满意度密切相关。未来的研究应评估综合癌症护理服务对患者生活质量满意度的影响。

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