Stork Alexander D M, van Haeften Timon W, Veneman Thiemo F
Department of Internal Medicine and Metabolic Diseases, University Medical Center Utrecht, Utrecht, The Netherlands.
Diabetes Care. 2007 Nov;30(11):2822-6. doi: 10.2337/dc06-1544. Epub 2007 Aug 8.
In recent years, there has been an ongoing discussion on the relationship between diabetes and driving. As driving performance will inevitably decline at lower levels of glycemia, patients' decisions concerning driving or taking corrective action when hypoglycemia occurs immediately before or during driving seems paramount.
Twenty-four type 1 diabetic patients with normal awareness of hypoglycemia (T1Norm group), 21 type 1 diabetic patients with impaired awareness of hypoglycemia (T1Imp group), and 20 type 2 diabetic patients with normal awareness of hypoglycemia (T2 group) were studied. They were asked whether they felt hypoglycemic and whether they would currently drive during experimental euglycemia (5.0 mmol/l) and hypoglycemia (2.7 mmol/l).
In the T1Norm group, 1 patient (4.2%) decided to drive during hypoglycemia. In the T1Imp group, 9 patients (42.9%) said they would drive in the hypoglycemic condition. In the T2 group, 5 patients (25%) would drive. This was more frequently the case for patients on oral hypoglycemic agents (chi2 = 4.44; P = 0.04). No effect of sex (chi2 = 0.78; P = 0.38) or age (chi2 = 0.22; P = 0.64) was noted.
Patients with type 1 diabetes and impaired awareness of hypoglycemia frequently decided to drive while hypoglycemic, whereas patients with type 1 diabetes and normal awareness of hypoglycemia appeared to make safe decisions concerning hypoglycemia and driving. Strikingly, patients with type 2 diabetes and normal hypoglycemia awareness frequently made potentially dangerous decisions as well, particularly when using oral hypoglycemic agents. Therefore, early, clear, and consistent education is imperative.
近年来,关于糖尿病与驾驶之间的关系一直存在讨论。由于血糖水平较低时驾驶表现必然会下降,患者在低血糖恰好在驾驶前或驾驶期间发生时关于是否驾驶或采取纠正措施的决定似乎至关重要。
对24名低血糖意识正常的1型糖尿病患者(T1Norm组)、21名低血糖意识受损的1型糖尿病患者(T1Imp组)和20名低血糖意识正常的2型糖尿病患者(T2组)进行了研究。在实验性血糖正常(5.0毫摩尔/升)和低血糖(2.7毫摩尔/升)状态下,询问他们是否感觉低血糖以及他们当时是否会开车。
在T1Norm组中,1名患者(4.2%)决定在低血糖时开车。在T1Imp组中,9名患者(42.9%)表示他们会在低血糖状态下开车。在T2组中,5名患者(25%)会开车。口服降糖药的患者更常出现这种情况(χ² = 4.44;P = 0.04)。未发现性别(χ² = 0.78;P = 0.38)或年龄(χ² = 0.22;P = 0.64)有影响。
低血糖意识受损的1型糖尿病患者经常在低血糖时决定开车,而低血糖意识正常的1型糖尿病患者在低血糖和驾驶方面似乎能做出安全的决定。引人注目的是,低血糖意识正常的2型糖尿病患者也经常做出潜在危险的决定,尤其是在使用口服降糖药时。因此,早期、明确且一致的教育势在必行。