Achrekar S, Kaklij G S, Pote M S, Kelkar S M
Biochemistry Division, Bhabha Atomic Research Centre, Bombay, India.
In Vivo. 1991 Mar-Apr;5(2):143-7.
The extract of jaman pulp from fruit of Eugenia jambolana showed hypoplycemic activity. This report is the first evidence of such activity in relation to pulp. The effect of pulp was seen in 30 min, while the seeds of the same fruit required 24 hr. The extracts of bark of Ficus bengalensis caused reduction in blood sugar level. These results were confirmed in streptozotocin-induced diabetic animals. The oral administration of the extract resulted in enhancement in serum insulin levels in normoglycemic and diabetic rats. The incubation of isolated islets of Langerhans from normal as well as from diabetic animals with each of these plant extracts stimulated insulin secretion. These extracts inhibited insulinase activity from liver and kidney.
来自蒲桃果实的蒲桃果肉提取物具有降血糖活性。本报告是关于果肉这种活性的首个证据。在30分钟内可见果肉的效果，而同一果实的种子则需要24小时。孟加拉榕树皮提取物可使血糖水平降低。这些结果在链脲佐菌素诱导的糖尿病动物中得到证实。提取物的口服给药导致正常血糖和糖尿病大鼠的血清胰岛素水平升高。用这些植物提取物中的每一种对来自正常和糖尿病动物的分离胰岛进行孵育，均刺激了胰岛素分泌。这些提取物抑制肝脏和肾脏的胰岛素酶活性。
