一名患有硬皮病的女性在复发性重度子痫前期后使用一氧化氮供体和肝素成功妊娠。

Successful pregnancy with the use of nitric oxide donors and heparin after recurrent severe preeclampsia in a woman with scleroderma.

作者信息

Carbonne Bruno, Macé Guillaume, Cynober Evelyne, Milliez Jacques, Cabane Jean

机构信息

Department of Obstetrics and Gynecology, Hôpital Saint-Antoine, Paris, France.

出版信息

Am J Obstet Gynecol. 2007 Aug;197(2):e6-7. doi: 10.1016/j.ajog.2007.04.025.

DOI:10.1016/j.ajog.2007.04.025

PMID:17689619

Abstract

We report the case of a woman with scleroderma who had severe, early-onset preeclampsia on 2 consecutive pregnancies. With a treatment that included aspirin, heparin, and a nitric oxide donor, her third pregnancy ended with a healthy neonate at term. Nitric oxide donors and heparin may play a preventive role on placental dysfunction in scleroderma.

摘要

我们报告了一例硬皮病女性患者的病例，该患者在连续两次妊娠时均出现严重的早发型子痫前期。通过包括阿司匹林、肝素和一氧化氮供体在内的治疗，她的第三次妊娠足月产下一名健康新生儿。一氧化氮供体和肝素可能对硬皮病患者的胎盘功能障碍起到预防作用。