Wang Chin-Chou, Wu Chao-Chien, Liu Jien-Wei, Lin An-Shen, Liu Shih-Feng, Chung Yu-Hsiu, Su Mao-Chang, Lee Ing-Kit, Lin Meng-Chih
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, 123 Dabi Road, Niaosung Shiang, Kaohsiung, Taiwan.
Am J Trop Med Hyg. 2007 Aug;77(2):291-6.
There has been no previously reported case series study regarding chest radiographic (CXR) presentations in dengue hemorrhagic fever (DHF) patients. We retrospectively studied 363 DHF patients from June to December 2002 in southern Taiwan, and a total of 468 CXRs were obtained and reviewed. More than 50% of these showed abnormalities after the 3rd day, with infiltration only and small pleural effusion as the major findings. Progressive changes during the first week and improvements during the second week were observed in these abnormal CXRs. The CXR presentation was also significantly correlated with laboratory findings (white blood cell count, platelet levels, activated partial thromboplastin time, and alanine aminotransferase and albumin levels), as well as the clinical course (renal insufficiency, liver function impairment, upper gastrointestinal bleeding, combination bacterial infection, and duration of admission) and outcome (mortality). The CXR may therefore be a modality for evaluating the clinical course of DHF and should be made during first week after the onset of illness.
此前尚无关于登革出血热（DHF）患者胸部X线（CXR）表现的病例系列研究报道。我们回顾性研究了2002年6月至12月台湾南部的363例DHF患者，共获得并分析了468份胸部X线片。其中超过50%的患者在第3天后出现异常，主要表现为单纯浸润和少量胸腔积液。这些异常胸部X线片在第一周呈现进行性变化，第二周有所改善。胸部X线表现还与实验室检查结果（白细胞计数、血小板水平、活化部分凝血活酶时间、丙氨酸转氨酶和白蛋白水平）、临床病程（肾功能不全、肝功能损害、上消化道出血、合并细菌感染及住院时间）及预后（死亡率）显著相关。因此，胸部X线检查可能是评估登革出血热临床病程的一种方式，应在发病后第一周内进行。
