Chlumská A, Chlumský J, Skála I, Marecková O, Pechancová J
II. patologickoanatomický ústav 1. LF Univerzity Karlovy, Praha.
Cas Lek Cesk. 1991 Oct 18;130(16-17):497-500.
In bioptic specimens of the gastric mucosa of 57 patients with dyspeptic complaints and/or a duodenal ulcer Helicobacter pylori was detected under the microscope in 82,4% of chronic active gastritis and in 28,6% and 61,5% resp. of chronic gastritis grade I and II. The finding of helicobacteria depended on the number of collected specimens. They were never found at sites with intestinal metaplasia and their numbers did not correspond to the intensity and character of the inflammatory changes. As compared with the antrum, in the corpus of the stomach helicobacteria were found more frequently not only in mild forms of the inflammation but also in the normal mucosa. In the duodenum the finding was negative and the inflammatory changes were only mild. In all patients with a duodenal ulcer and a scar after ulceration in the antrum chronic active or inactive gastritis grade II was found with helicobacteria in 84,6% of the observations. Cultivation was consistent with microscopic evidence in 50 patients (87,7%).
在对57例有消化不良症状和/或十二指肠溃疡的患者的胃黏膜活检标本进行检查时，显微镜下发现，幽门螺杆菌在82.4%的慢性活动性胃炎患者中被检测到，在Ⅰ级和Ⅱ级慢性胃炎患者中分别为28.6%和61.5%。螺旋杆菌的检出取决于所采集标本的数量。在肠化生部位从未发现过螺旋杆菌，其数量与炎症变化的强度和特征也不相符。与胃窦相比，在胃体部，螺旋杆菌不仅在轻度炎症形式中更频繁地被发现，在正常黏膜中也更常见。在十二指肠中，检查结果为阴性，炎症变化仅为轻度。在所有患有十二指肠溃疡且胃窦有溃疡后瘢痕的患者中，84.6%的观察结果显示存在伴有螺旋杆菌的Ⅱ级慢性活动性或非活动性胃炎。50例患者（87.7%）的培养结果与显微镜检查结果一致。
