Hogle William P
UPMC Passavant Cancer Center, Pittsburgh, PA, USA.
Semin Oncol Nurs. 2007 Aug;23(3):213-24. doi: 10.1016/j.soncn.2007.05.006.
To provide a review of the literature of commonly prescribed cytoprotective agents used in the treatment of patients with cancer.
Journal articles, research reports, review articles, and web sites.
Multiple agents have been theorized to have cytoprotective properties. Significant evidence exists supporting the use of some cytoprotective agents approved by the US Food and Drug Administration (FDA). More research is needed to determine the efficacy of new cytoprotective agents and expanded indications for those agents currently used.
Knowledge of the indications for and side effect profiles of cytoprotective agents is a necessary component of oncology nursing care. Familiarity with evidence-based research that supports or refutes the use of FDA-approved cytoprotective agents or alternative agents is helpful when suggesting, prescribing, or administering such agents.
综述常用于治疗癌症患者的细胞保护剂的文献。
期刊文章、研究报告、综述文章及网站。
多种药物被认为具有细胞保护特性。有大量证据支持使用美国食品药品监督管理局(FDA)批准的一些细胞保护剂。需要更多研究来确定新型细胞保护剂的疗效以及扩大目前所用药物的适应证。
了解细胞保护剂的适应证和副作用概况是肿瘤护理的必要组成部分。在建议、开处方或使用此类药物时,熟悉支持或反驳使用FDA批准的细胞保护剂或替代药物的循证研究很有帮助。