Kong Yu X, Wright Gavin, Pesudovs Konrad, O'Day Justin, Wainer Zoe, Weisinger Harrison S
Cardiothoracic Care Centre, Fitzroy, Victoria, Australia.
Clin Exp Optom. 2007 Sep;90(5):336-44. doi: 10.1111/j.1444-0938.2007.00177.x.
Horner syndrome is an uncommon but important clinical entity, representing interruption of the sympathetic pathway to the eye and face. Horner syndrome is almost always diagnosed clinically, though pharmacological testing can be used to confirm the diagnosis. Imaging modalities such as PET, CT and MRI are important components of work-up for patients presenting with acquired Horner syndrome. Our patient's presentation with Horner syndrome unmasked the causative superior sulcus squamous cell carcinoma and a coincidental lower lobe adenocarcinoma. Successful radical treatment of these cancers resulted in complete resolution of the syndrome and disease-free survival at 18 months. We review the anatomy and pathophysiology underlying this and other causes of Horner syndrome.
霍纳综合征是一种罕见但重要的临床病症，表现为通往眼部和面部的交感神经通路中断。霍纳综合征几乎总是通过临床诊断，不过药理学检测可用于确诊。正电子发射断层扫描（PET）、计算机断层扫描（CT）和磁共振成像（MRI）等影像学检查手段是后天性霍纳综合征患者检查的重要组成部分。我们的患者表现出霍纳综合征，从而发现了导致该综合征的肺上沟鳞状细胞癌以及同时存在的下叶腺癌。对这些癌症的成功根治使综合征完全缓解，并实现了18个月的无病生存。我们回顾了霍纳综合征及其他病因背后的解剖学和病理生理学知识。
