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甲状腺手术后的霍纳综合征。

Horner's Syndrome Following Thyroid Surgery.

作者信息

Arishi Abdulaziz A, Abualhana Farouk, Sferra Joseph

机构信息

General Surgery, Faculty of Medicine, Jazan University, Jazan, SAU.

General Surgery, The University of Toledo College of Medicine and Life Sciences, Toledo, USA.

出版信息

Cureus. 2023 Sep 23;15(9):e45825. doi: 10.7759/cureus.45825. eCollection 2023 Sep.

DOI:10.7759/cureus.45825
PMID:37876407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10591229/
Abstract

Horner's syndrome (HS) is a rare complication of thyroidectomy caused by damage to the oculosympathetic nerves. This article reports the case of a 29-year-old woman referred to the clinic with a newly diagnosed papillary thyroid carcinoma (PTC). Ultrasound studies were concerning for multiple thyroid nodules and an enlarged lymph node, confirmed by a computed tomography (CT) scan. Cytology results of fine needle aspiration (FNA) diagnostic for PTC showed tumors in the thyroid tissue and lymph node. The patient underwent a thyroidectomy and woke up with right-sided ptosis and miosis. Clinical follow-up revealed subjective ipsilateral anhidrosis. She also developed a low parathyroid hormone level and dysphonia, albeit they resolved after months. The patient still exhibits HS eight months after surgery. This paper reviews the literature and attempts to establish the most probable causal factor while providing implications for surgical teams to minimize HS occurrence in future thyroid surgeries.

摘要

霍纳综合征(HS)是甲状腺切除术后一种罕见的并发症,由眼交感神经受损引起。本文报告了一名29岁女性的病例,该患者因新诊断出的甲状腺乳头状癌(PTC)前来诊所就诊。超声检查发现多个甲状腺结节和一个肿大的淋巴结,计算机断层扫描(CT)证实了这一情况。细针穿刺抽吸(FNA)诊断为PTC的细胞学结果显示甲状腺组织和淋巴结中有肿瘤。患者接受了甲状腺切除术,术后醒来出现右侧上睑下垂和瞳孔缩小。临床随访发现同侧有主观无汗。她还出现了甲状旁腺激素水平低和声音嘶哑的症状,不过数月后这些症状都消失了。术后八个月,该患者仍表现出霍纳综合征。本文回顾了相关文献,试图确定最可能的病因,同时为手术团队提供建议,以尽量减少未来甲状腺手术中霍纳综合征的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a49a/10591229/cb0221ceecba/cureus-0015-00000045825-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a49a/10591229/cb0221ceecba/cureus-0015-00000045825-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a49a/10591229/cb0221ceecba/cureus-0015-00000045825-i01.jpg

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Horner's Syndrome Following Thyroid Surgery.甲状腺手术后的霍纳综合征。
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引用本文的文献

1
Horner's Syndrome as a Rare Complication of Thyroidectomy With Central Neck Dissection: A Case Report and Review of Potential Mechanisms.霍纳综合征作为甲状腺切除术加中央区颈清扫术的罕见并发症:一例报告及潜在机制综述
Cureus. 2025 Feb 11;17(2):e78841. doi: 10.7759/cureus.78841. eCollection 2025 Feb.

本文引用的文献

1
Horner syndrome as a complication after thyroid microwave ablation: Case report and brief literature review.甲状腺微波消融术后并发霍纳综合征:病例报告及文献简要综述
Medicine (Baltimore). 2018 Aug;97(34):e11884. doi: 10.1097/MD.0000000000011884.
2
Horner syndrome as a postoperative complication after minimally invasive video-assisted thyroidectomy: A case report.霍纳综合征作为微创电视辅助甲状腺切除术后的一种术后并发症:一例报告。
Medicine (Baltimore). 2017 Dec;96(48):e8888. doi: 10.1097/MD.0000000000008888.
3
Horner Syndrome Secondary to Thyroid Surgery.
甲状腺手术后继发霍纳综合征
Case Rep Endocrinol. 2017;2017:1689039. doi: 10.1155/2017/1689039. Epub 2017 Jan 4.
4
Horner Syndrome Following Thyroid Surgery: The Clinical and Pharmacological Presentations.甲状腺手术后的霍纳综合征:临床与药理学表现
J Ophthalmic Vis Res. 2016 Oct-Dec;11(4):442-444. doi: 10.4103/2008-322X.194146.
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American Thyroid Association statement on preoperative imaging for thyroid cancer surgery.美国甲状腺协会关于甲状腺癌手术术前影像学检查的声明。
Thyroid. 2015 Jan;25(1):3-14. doi: 10.1089/thy.2014.0096.
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Horner's syndrome as a complication of thyroidectomy: report of a case.霍纳综合征作为甲状腺切除术的并发症:一例报告。
Surg Today. 2008;38(12):1114-6. doi: 10.1007/s00595-007-3741-z. Epub 2008 Nov 28.
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Horner syndrome.霍纳综合征。
Clin Exp Optom. 2007 Sep;90(5):336-44. doi: 10.1111/j.1444-0938.2007.00177.x.
8
Horner's syndrome in association with thyroid and parathyroid disease.霍纳综合征与甲状腺及甲状旁腺疾病相关。
ANZ J Surg. 2004 Jun;74(6):442-5. doi: 10.1111/j.1445-1433.2004.03030.x.