de Fontbrune F S, Mal H, Dauriat G, Brugière O, Biondi G, Taillé C, Valla D, Castier Y, Fournier M
Service de Pneumologie B et Transplantation Pulmonaire, Hôpital Bichat, Paris, France.
Am J Transplant. 2007 Sep;7(9):2208-11. doi: 10.1111/j.1600-6143.2007.01913.x.
Veno-occlusive disease (VOD) of the liver is mainly described after chemo-irradiation conditioning regimens during haematopoietic stem cell transplantation (SCT) and has been sporadically reported after kidney and liver transplantation. In the latter cases, it is commonly attributed to azathioprine and/or tacrolimus. One case of tacrolimus-induced hepatic VOD developing after lung transplantation (LT) has been recently reported. Here we describe another case of VOD occurring after LT, but in which the causative role was played by azathioprine.
肝静脉闭塞病（VOD）主要见于造血干细胞移植（SCT）期间接受化疗放疗预处理方案后，在肾移植和肝移植后也有零星报道。在后一种情况下，通常归因于硫唑嘌呤和/或他克莫司。最近有一例肺移植（LT）后发生他克莫司诱导的肝VOD的病例报道。在此，我们描述另一例LT后发生的VOD病例，但病因是硫唑嘌呤。
