Whitaker Robert C, Orzol Sean M, Kahn Robert S
Mathematica Policy Research, Inc., Princeton, NJ, USA.
Prev Med. 2007 Dec;45(6):476-80. doi: 10.1016/j.ypmed.2007.07.005. Epub 2007 Jul 14.
To examine the association between maternal smoking 15 months after delivery and the occurrence of a major depressive episode in the prior 12 months.
Data were obtained from the Fragile Families and Child Wellbeing Study, a birth cohort study. In 20 U.S. cities, 4898 mothers were surveyed at delivery in the years 1998 to 2000. In a survey 15 months later, 4353 (89%) of the mothers reported their smoking behavior and symptoms of a major depressive episode during the prior 12 months.
At the follow-up survey, 26.6% of mothers reported that they were current smokers and 13.6% reported that they had symptoms of a major depressive episode during the prior 12 months. After adjusting for sociodemographic characteristics, the prevalence (95% confidence interval) of a major depressive episode was higher among smokers than nonsmokers: 17.7% (15.7%, 19.8%) vs. 12.1% (10.9%, 13.3%). Smoking was also more common among mothers with a major depressive episode than in those without one: 34.0% (30.6%, 37.4%) vs. 25.5% (24.1%, 26.8%).
Smoking and depression often co-occur among mothers with infants. This suggests that these conditions should not be diagnosed or treated in isolation from each other and that the care of mothers and children should be integrated.
研究产后15个月时母亲吸烟与前12个月内发生重度抑郁发作之间的关联。
数据来自脆弱家庭与儿童健康研究，这是一项出生队列研究。在1998年至2000年期间，在美国20个城市对4898名母亲进行了分娩时的调查。15个月后的一项调查中，4353名（89%）母亲报告了她们的吸烟行为以及前12个月内的重度抑郁发作症状。
在随访调查中，26.6%的母亲报告称她们目前吸烟，13.6%的母亲报告称在前12个月内有重度抑郁发作症状。在对社会人口学特征进行调整后，吸烟者中重度抑郁发作的患病率（95%置信区间）高于不吸烟者：17.7%（15.7%，19.8%）对12.1%（10.9%，13.3%）。有重度抑郁发作的母亲中吸烟也比没有发作的母亲更常见：34.0%（30.6%，37.4%）对25.5%（24.1%，26.8%）。
吸烟和抑郁在有婴儿的母亲中经常同时出现。这表明这些情况不应孤立地进行诊断或治疗，母亲和儿童的护理应该整合起来。
