Park Elyse R, Chang Yuchiao, Quinn Virginia, Regan Susan, Cohen Lee, Viguera Adele, Psaros Christina, Ross Kaile, Rigotti Nancy
Tobacco Research and Treatment Center, Institute for Health Policy, and Department of Psychiatry, Massachusetts General Hospital, 50 Staniford Street, 9th floor, Boston, MA 02114, USA.
Nicotine Tob Res. 2009 Jun;11(6):707-14. doi: 10.1093/ntr/ntp053. Epub 2009 May 12.
The aim of this prospective repeated measures, mixed-methods observational study was to assess whether depressive, anxiety, and stress symptoms are associated with postpartum relapse to smoking.
A total of 65 women who smoked prior to pregnancy and had not smoked during the last month of pregnancy were recruited at delivery and followed for 24 weeks. Surveys administered at baseline and at 2, 6, 12, and 24 weeks postpartum assessed smoking status and symptoms of depression (Beck Depression Inventory [BDI]), anxiety (Beck Anxiety Inventory [BAI]), and stress (Perceived Stress Scale [PSS]). In-depth interviews were conducted with women who reported smoking.
Although 92% of the participants reported a strong desire to stay quit, 47% resumed smoking by 24 weeks postpartum. Baseline factors associated with smoking at 24 weeks were having had a prior delivery, not being happy about the pregnancy, undergoing counseling for depression or anxiety during pregnancy, and ever having struggled with depression (p < .05). In a repeated measures regression model, the slope of BDI scores from baseline to the 12-week follow-up differed between nonsmokers and smokers (-0.12 vs. +0.11 units/week, p = .03). The slope of PSS scores also differed between nonsmokers and smokers (-0.05 vs. +0.08 units/week, p = .04). In qualitative interviews, most women who relapsed attributed their relapse and continued smoking to negative emotions.
Among women who quit smoking during pregnancy, a worsening of depressive and stress symptoms over 12 weeks postpartum was associated with an increased risk of smoking by 24 weeks.
这项前瞻性重复测量、混合方法的观察性研究旨在评估抑郁、焦虑和压力症状是否与产后复吸有关。
共有65名在怀孕前吸烟且在怀孕最后一个月未吸烟的女性在分娩时被招募,并随访24周。在基线以及产后2周、6周、12周和24周进行的调查评估了吸烟状况以及抑郁症状(贝克抑郁量表[BDI])、焦虑症状(贝克焦虑量表[BAI])和压力症状(感知压力量表[PSS])。对报告吸烟的女性进行了深入访谈。
尽管92%的参与者表示有强烈的戒烟意愿,但47%的人在产后24周时恢复吸烟。与产后24周吸烟相关的基线因素包括既往有分娩史、对怀孕不满意、在孕期接受过抑郁或焦虑咨询以及曾患抑郁症(p<0.05)。在重复测量回归模型中,非吸烟者和吸烟者从基线到12周随访期间BDI评分的斜率不同(-0.12对+0.11单位/周,p = 0.03)。PSS评分的斜率在非吸烟者和吸烟者之间也有所不同(-0.05对+0.08单位/周,p = 0.04)。在定性访谈中,大多数复吸的女性将她们的复吸和持续吸烟归因于负面情绪。
在孕期戒烟的女性中,产后12周内抑郁和压力症状的恶化与产后24周吸烟风险增加有关。