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一株火鸡呼吸道腺病毒的分离与鉴定

Isolation and identification of a turkey respiratory adenovirus.

作者信息

Simmons D G, Miller S E, Gray J G, Blalock H G, Colwell W M

出版信息

Avian Dis. 1976 Jan-Mar;20(1):65-74.

PMID:176992
Abstract

A virus with physical and biological characteristics of an adenovirus was isolated from turkey poults with respiratory disease. The virus was ether-resistant and incorporated [3H] thymidine. Electron microscopy revealed virions of icosahedral configuration, approximately 78 nm in diameter, within the nuclei of infected cells. The virus produced cytopathology in turkey kidney cells, but did not produce observable disease when inoculated into commercial turkey poults or specific-pathogen-free embryonated chicken eggs. Virus-neutralization tests indicated widespread exposure to the virus in North Carolina turkey populations.

摘要

从患有呼吸道疾病的小火鸡中分离出一种具有腺病毒物理和生物学特性的病毒。该病毒对乙醚具有抗性,并能掺入[3H]胸苷。电子显微镜检查显示,在受感染细胞的细胞核内有直径约78纳米的二十面体构型病毒粒子。该病毒在火鸡肾细胞中产生细胞病变,但接种到商用小火鸡或无特定病原体的鸡胚中时未产生明显疾病。病毒中和试验表明,北卡罗来纳州的火鸡群体普遍接触过这种病毒。

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