大序列多态性可对具有祖传间隔寡核苷酸分型模式的结核分枝杆菌菌株进行分类。
Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns.
作者信息
Flores Laura, Van Tran, Narayanan Sujatha, DeRiemer Kathryn, Kato-Maeda Midori, Gagneux Sebastien
机构信息
Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, USA.
出版信息
J Clin Microbiol. 2007 Oct;45(10):3393-5. doi: 10.1128/JCM.00828-07. Epub 2007 Aug 15.
Abstract
Genomic deletion analysis revealed that strains of Mycobacterium tuberculosis exhibiting spoligotyping patterns with almost all spacers present belong either to a strain lineage that includes the W-Beijing strain family or to the ancestral strain lineage of M. tuberculosis.
摘要
基因组缺失分析表明，结核分枝杆菌菌株若呈现几乎所有间隔区都存在的寡核苷酸分型模式，则要么属于包含W-北京菌株家族的菌株谱系，要么属于结核分枝杆菌的祖先菌株谱系。
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