Finkel Toren, Serrano Manuel, Blasco Maria A
Cardiology Branch, NIH, NHLBI, Building 10/CRC 5-3330, 10 Center Drive, Bethesda, Maryland 20892, USA.
Nature. 2007 Aug 16;448(7155):767-74. doi: 10.1038/nature05985.
At first glance, cancer and ageing would seem to be unlikely bedfellows. Yet the origins for this improbable union can actually be traced back to a sequence of tragic--and some say unethical--events that unfolded more than half a century ago. Here we review the series of key observations that has led to a complex but growing convergence between our understanding of the biology of ageing and the mechanisms that underlie cancer.
乍一看，癌症与衰老似乎不太可能联系在一起。然而，这种不太可能的结合的根源实际上可以追溯到半个多世纪前发生的一系列悲惨事件——有人认为这些事件是不道德的。在这里，我们回顾了一系列关键观察结果，这些结果导致了我们对衰老生物学的理解与癌症潜在机制之间复杂但日益趋同的认识。
