Wang Xiupeng, Ye Jiandong
Key Laboratory of Specially Functional Materials, South China University of Technology, Ministry of Education, Guangzhou 510641, China.
J Mater Sci Mater Med. 2008 Mar;19(3):1183-6. doi: 10.1007/s10856-007-3209-0. Epub 2007 Aug 15.
New routes were used to introduce strontium into calcium phosphate cement in the present article. The study showed that by mixing 50 wt% amorphous calcium phosphate + amorphous strontium phosphate and 50 wt% dicalcium phosphate dihydrate, hydroxyapatite and Sr-hydroxyapatite precipitated separately in the hydrated cement; whereas, by mixing 50 wt% Sr- amorphous calcium phosphate and 50 wt% dicalcium phosphate dihydrate, strontium can be doped into hydroxyapatite lattice and increase the lattice dimensions and lattice volume. The strontium substituted calcium phosphate cement has potential for use in orthopedic surgeries.
在本文中，采用了新的方法将锶引入磷酸钙骨水泥。研究表明，通过混合50 wt%的无定形磷酸钙+无定形磷酸锶和50 wt%的二水磷酸二钙，水合骨水泥中分别沉淀出羟基磷灰石和锶羟基磷灰石；而通过混合50 wt%的锶-无定形磷酸钙和50 wt%的二水磷酸二钙，锶可以掺入羟基磷灰石晶格中，增加晶格尺寸和晶格体积。锶取代的磷酸钙骨水泥在骨科手术中具有应用潜力。
