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在去卵巢大鼠的更年期综合征模型中,回收棕榈油在维持骨骼特性方面优于大豆油。

Recycled palm oil is better than soy oil in maintaining bone properties in a menopausal syndrome model of ovariectomized rat.

作者信息

Shuid Ahmad Nazrun, Chuan Loh Hong, Mohamed Norazlina, Jaarin Kamsiah, Fong Yew Su, Soelaiman Ima Nirwana

机构信息

Department of Phamacology, Faculty of Medicine UKM, Universiti Kebangsaan Malaysia, Jln Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

出版信息

Asia Pac J Clin Nutr. 2007;16(3):393-402.

Abstract

Palm oil is shown to have antioxidant, anticancer and cholesterol lowering effects. It is resistant to oxidation when heated compared to other frying oils such as soy oil. When a frying oil is heated repeatedly, it forms toxic degradation products, such as aldehydes which when consumed, may be absorbed into the systemic circulation. We have studied the effects of taking soy or palm oil that were mixed with rat chow on the bone histomorphometric parameters of ovariectomised rats. Female Sprague-Dawley rats were divided into eight groups: (1) normal control group; (2) ovariectomised-control group; (3) ovariectomised and fresh soy oil; (4) ovariectomised and soy oil heated once; (5) ovariectomised and soy oil heated five times; (6) ovariectomised and fresh palm oil; (7) ovariectomised and palm oil heated once; (8) ovariectomised and palm oil heated five times. These oils were mixed with rat chow at weight ratio of 15:100 and were given to the rats daily for six months. Ovariectomy had caused negative effects on the bone histomorphometric parameters. Ingestion of both fresh and once-heated oils, were able to offer protections against the negative effects of ovariectomy, but these protections were lost when the oils were heated five times. Soy oil that was heated five times actually worsens the histomorphometric parameters of ovariectomised rats. Therefore, it may be better for postmenopausal who are at risk of osteoporosis to use palm oil as frying oil especially if they practice recycling of frying oils.

摘要

已表明棕榈油具有抗氧化、抗癌和降低胆固醇的作用。与其他煎炸油如大豆油相比,它在加热时抗氧化。当一种煎炸油反复加热时,会形成有毒的降解产物,如醛类,食用后可能会被吸收进入体循环。我们研究了将大豆油或棕榈油与大鼠饲料混合后对去卵巢大鼠骨组织形态计量学参数的影响。雌性Sprague-Dawley大鼠分为八组:(1)正常对照组;(2)去卵巢对照组;(3)去卵巢与新鲜大豆油组;(4)去卵巢与加热一次的大豆油组;(5)去卵巢与加热五次的大豆油组;(6)去卵巢与新鲜棕榈油组;(7)去卵巢与加热一次的棕榈油组;(8)去卵巢与加热五次的棕榈油组。这些油以15:100的重量比与大鼠饲料混合,每天喂给大鼠,持续六个月。去卵巢对骨组织形态计量学参数产生了负面影响。摄入新鲜油和加热一次的油都能够对抗去卵巢的负面影响,但当油加热五次时,这些保护作用就丧失了。加热五次的大豆油实际上会使去卵巢大鼠的组织形态计量学参数恶化。因此,对于有骨质疏松风险的绝经后女性来说,使用棕榈油作为煎炸油可能更好,尤其是如果她们有重复使用煎炸油的习惯。

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