拓展对蛋白质的理解——蛋白质数据库综述
Stretching to understand proteins - a survey of the protein data bank.
作者信息
Sułkowska Joanna I, Cieplak Marek
机构信息
Institute of Physics, Polish Academy of Sciences, Warsaw, Poland.
出版信息
Biophys J. 2008 Jan 1;94(1):6-13. doi: 10.1529/biophysj.107.105973. Epub 2007 Aug 17.
Abstract
We make a survey of resistance of 7510 proteins to mechanical stretching at constant speed as studied within a coarse-grained molecular dynamics model. We correlate the maximum force of resistance with the native structure, predict proteins which should be especially strong, and identify the nature of their force clamps.
摘要
我们在粗粒度分子动力学模型中，对7510种蛋白质在恒速下的机械拉伸抗性进行了研究。我们将最大抗性力与天然结构相关联，预测哪些蛋白质应该特别强，并确定其力钳的性质。
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