Doré Elizabeth, Fecteau Gilles, Hélie Pierre, Francoz David
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
J Vet Intern Med. 2007 Jul-Aug;21(4):853-6.
The characteristic clinical manifestations, clinicopathologic findings, treatment, and outcome of dairy cattle with liver abscess are poorly defined.
The study included 18 Holstein cows with liver abscesses.
A retrospective study of medical records was performed. Cattle with liver abscess were identified by ultrasound examination or exploratory laparotomy.
The most common reason for examination was anorexia (14/18). Five cows had fever, 5 were bradycardic, and 5 were tachycardic. Peritonitis (n=6) and vagal indigestion (n=4) were the most frequently associated diseases. Neutrophilia (n=14), hyperfibrinogenemia (n=11), and high serum globulin concentration (n=10) were characteristic of chronic inflammation. Evidence of liver disease on serum biochemistry profile was uncommon. The most common bacterium isolated from the abscess was Arcanobacterium pyogenes (n=4). Anaerobic bacteria were isolated frequently (n=7). There were 6 polymicrobial isolates, with both aerobic and anaerobic bacteria, out of 8 positive samples. Medical treatment was successful in 5 of 7 cattle. Five cows were euthanized and postmortem examination revealed 2 cattle with thrombosis of caudal vena cava.
Holstein dairy cattle affected by liver abscess exhibit no pathognomonic clinical signs. Clinicopathologic findings were often consistent with a chronic active inflammation. Liver abscesses should be included in the differential diagnosis in cattle with a chronic inflammatory process, cranial peritonitis, or vagal indigestion. Prolonged treatment with antimicrobials might be successful.
患有肝脓肿的奶牛的特征性临床表现、临床病理特征、治疗方法及预后尚不清楚。
本研究纳入了18头患有肝脓肿的荷斯坦奶牛。
对病历进行回顾性研究。通过超声检查或剖腹探查确定患有肝脓肿的牛。
检查的最常见原因是厌食（14/18）。5头牛发热，5头心动过缓，5头心动过速。腹膜炎（n = 6）和迷走神经性消化不良（n = 4）是最常伴发的疾病。中性粒细胞增多（n = 14）、高纤维蛋白原血症（n = 11）和高血清球蛋白浓度（n = 10）是慢性炎症的特征。血清生化指标显示肝脏疾病的证据并不常见。从脓肿中分离出的最常见细菌是化脓隐秘杆菌（n = 4）。厌氧菌经常被分离出来（n = 7）。在8份阳性样本中，有6份是需氧菌和厌氧菌的混合菌分离株。7头牛中有5头药物治疗成功。5头牛被安乐死，尸检显示2头牛有尾腔静脉血栓形成。
受肝脓肿影响的荷斯坦奶牛没有特征性的临床症状。临床病理特征通常与慢性活动性炎症一致。对于患有慢性炎症过程、颅部腹膜炎或迷走神经性消化不良的牛，肝脓肿应列入鉴别诊断。长期使用抗菌药物治疗可能会成功。
