Archaeosomes based on synthetic tetraether-like lipids as novel versatile gene delivery systems.
作者信息
Réthoré G, Montier T, Le Gall T, Delépine P, Cammas-Marion S, Lemiègre L, Lehn P, Benvegnu T
机构信息
ENSCR, UMR CNRS 6226 Sciences Chimiques de Rennes, Equipe Synthèse Organique et Systèmes Organises, 35700 Rennes, France.
出版信息
Chem Commun (Camb). 2007 May 28(20):2054-6. doi: 10.1039/b618568a.
DOI:10.1039/b618568a
PMID:17713076
Abstract
Novel cationic liposomes, termed "archaeosomes", based on mixtures of neutral/cationic bilayer-forming lipids and archaeobacterial synthetic tetraether-type bipolar lipids show efficient in vitro gene transfection properties and represent a new approach for modulating the lipidic membrane fluidity of the complexes they form with DNA.
摘要
Zotero 插件