Rebel A, Malkani K, Baslé M, Bregeon C
Calcif Tissue Res. 1976 Apr 20(2):187-99. doi: 10.1007/BF02546407.
The ultrastructural study of osteoclasts in biopsies from 12 patients with Paget's disease reveals several cytological anomalies. In Particular, nuclear inclusions, consisting essentially of striated filaments about 150 A in diameter, often organized in bundles and sometimes in paracrystalline arrays, appear to be specific to the disease. Morphologically, the inclusions are remarkably similar to those observed in various cases of viral attack, and the hypothesis of the action of a possible external agent in Paget's disease cannot be ruled out.
对12例佩吉特病患者活检组织中的破骨细胞进行超微结构研究，发现了一些细胞学异常。特别是核内包涵体，主要由直径约150埃的横纹丝组成，常成束排列，有时呈副晶状排列，似乎是该病所特有的。从形态学上看，这些包涵体与在各种病毒感染病例中观察到的包涵体非常相似，因此不能排除在佩吉特病中可能存在外部致病因素作用的假说。
