Rawdaree Petch, Ngarmukos Chardpraorn, Deerochanawong Chaicharn, Suwanwalaikorn Sompongse, Chetthakul Thanya, Krittiyawong Sirinate, Benjasuratwong Yupin, Bunnag Pongamorn, Kosachunhanun Natapong, Plengvidhya Nattachet, Leelawatana Rattana, Prathipanawatr Thongchai, Likitmaskul Supawadee, Mongkolsomlit Sirima
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2006 Aug;89 Suppl 1:S1-9.
The primary objectives of the Thailand Diabetes Registry project were to identify the characteristics of Thai diabetic patients in tertiary care medical centers and to determine the extent of long term diabetic complications. The secondary objective aimed at building up and strengthening clinical research network among Thai experts in diabetes mellitus and collection of baseline data for future follow-up study.
A cross-sectional, multi-center, hospital-based diabetes registry was carried out from diabetes clinics of 11 tertiary centers. Demographic data, clinical status of diabetes and its complications were collected and analyzed for the prevalence of complications and risk factors.
Nine-thousand-four-hundred-and-nineteen patients were registered for the project and 94.6% were type 2 diabetes. Mean +/- SD of age was 59.4 +/- 13.5 and duration of diabetes was and 10 +/- 7.6 years. Only 38.2% of the subjects achieved glycemic control of FPG under 130 mg/dl in only 30.7% had an HbA lc of less than 7%. The overall prevalence of dyslipidemia found in this population was 73.3%, hypertension was 63.3% and obesity (BMI >25 kg/m2) was 52.6%. Diabetic nephropathy was the most common complication accounting for 43.9% followed by retinopathy 30.7%, IHD 8.1% and cerebrovascular disease 4.4%.
The prevalence of dyslipidemia and hypertension were high in this population, which may be associated with the high prevalence of diabetic complications. The unsatisfactory control of metabolic status may be due to aging and long duration of diabetic patients in this registry.
泰国糖尿病登记项目的主要目标是确定三级医疗中心泰国糖尿病患者的特征,并确定长期糖尿病并发症的程度。次要目标是建立和加强泰国糖尿病专家之间的临床研究网络,并收集基线数据以供未来的随访研究。
在11个三级中心的糖尿病诊所开展了一项横断面、多中心、基于医院的糖尿病登记。收集并分析了人口统计学数据、糖尿病临床状况及其并发症,以了解并发症和危险因素的患病率。
该项目登记了9419名患者,其中94.6%为2型糖尿病。年龄的平均值±标准差为59.4±13.5岁,糖尿病病程为10±7.6年。只有38.2%的受试者空腹血糖(FPG)控制在130mg/dl以下,只有30.7%的糖化血红蛋白(HbA1c)低于7%。该人群中血脂异常的总体患病率为73.3%,高血压为63.3%,肥胖(体重指数>25kg/m2)为52.6%。糖尿病肾病是最常见的并发症,占43.9%,其次是视网膜病变30.7%,缺血性心脏病8.1%,脑血管疾病4.4%。
该人群中血脂异常和高血压的患病率较高,这可能与糖尿病并发症的高患病率有关。代谢状态控制不佳可能是由于该登记中糖尿病患者的老龄化和病程较长。