化疗引起的脱发及其对乳腺癌女性生活质量的影响：一项文献综述
Chemotherapy-induced alopecia and effects on quality of life among women with breast cancer: a literature review.
作者信息
Lemieux Julie, Maunsell Elizabeth, Provencher Louise
机构信息
Unité de recherche en santé des populations, Centre hospitalier affilié universitaire de Québec, Quebec, Que, Canada.
出版信息
Psychooncology. 2008 Apr;17(4):317-28. doi: 10.1002/pon.1245.
BACKGROUND
Alopecia is a common side effect of chemotherapies used in the treatment of breast cancer. The aim of this review is to describe the effects of alopecia on quality of life (QOL) in this population.
METHODS
We conducted a literature review using Medline, Embase, Cumulative Index to Nursing and Allied Health Literature and PsycInfo databases. We searched for studies on the effects of alopecia on various aspects of QOL in breast cancer patients including anxiety and distress, body image, sexuality, self-esteem, social functioning, global QOL and return to work outcomes.
RESULTS
A total of 38 articles were included in the review. Hair loss consistently ranked amongst the most troublesome side effects, was described as distressing, and may affect the body image.
CONCLUSIONS
We found very little quantitative data on other aspects of QOL. More research is needed to determine the presence and extent of negative effects on chemotherapy-induced alopecia on various aspects of QOL.
背景
脱发是乳腺癌治疗中常用化疗的常见副作用。本综述的目的是描述脱发对该人群生活质量（QOL）的影响。
方法
我们使用Medline、Embase、护理及相关健康文献累积索引和PsycInfo数据库进行了文献综述。我们搜索了关于脱发对乳腺癌患者生活质量各个方面影响的研究，包括焦虑和痛苦、身体形象、性功能、自尊、社会功能、总体生活质量和重返工作岗位的结果。
结果
本综述共纳入38篇文章。脱发一直被列为最麻烦的副作用之一，被描述为令人痛苦，并且可能影响身体形象。
结论
我们发现关于生活质量其他方面的定量数据非常少。需要更多的研究来确定化疗引起的脱发对生活质量各个方面负面影响存在与否及其程度。
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