Danielsson Aina J
Department of Orthopedics, Sahlgrenska University Hospital, Göteborg University, Göteborg, Sweden.
Spine (Phila Pa 1976). 2007 Sep 1;32(19 Suppl):S101-8. doi: 10.1097/BRS.0b013e318134ed0e.
: Literature review.
: To identify scientifically sound studies that have reported changes in quality of life (QOL) after spinal deformity correction in patients with adolescent idiopathic scoliosis (AIS) and to discuss these findings.
: Few studies have been published. Most are retrospective cohort studies and lack both preoperative and postoperative data for the outcome in terms of QOL.
: A review of existing literature with the emphasis on spinal fusion for AIS and outcome as measured by health-related QOL was performed.
: Thirteen studies of various quality were found after reviewing the papers. Only 3 of them contained both preoperative and postoperative data on QOL, using the SRS-22/-24. They all reported a statistically significant improvement in some of the domain scores. The clinical implications of these findings are unclear, as the minimal clinically important differences for SRS-22/-24 have not yet been established.
: Weak evidence (Level IV) exists in the literature that spinal deformity correction for AIS does not significantly impact QOL in short-term or mid-term. The interpretation of this must be that there were no serious adverse events after surgery.
文献综述。
识别科学合理的研究,这些研究报告了青少年特发性脊柱侧凸(AIS)患者脊柱畸形矫正后生活质量(QOL)的变化,并讨论这些发现。
已发表的研究很少。大多数是回顾性队列研究,缺乏术前和术后生活质量方面的结局数据。
对现有文献进行综述,重点关注AIS的脊柱融合术以及通过与健康相关的生活质量来衡量的结局。
在审阅论文后发现了13项质量各异的研究。其中只有3项使用SRS-22/-24包含术前和术后生活质量数据。它们均报告某些领域得分有统计学上的显著改善。由于尚未确定SRS-22/-24的最小临床重要差异,这些发现的临床意义尚不清楚。
文献中存在薄弱证据(IV级)表明,AIS的脊柱畸形矫正术在短期或中期不会显著影响生活质量。对此的解释必定是术后没有严重不良事件。